Purpose Recently, alterations in maternal lipid metabolism were associated with gestational
diabetes mellitus (GDM). However, detailed plasma lipid profiles and their relevance for …

Hepatic low density lipoprotein receptor (LDLR), 3-hydroxy-3-methylglutaryl coenyzme A
reductase (HMGR), cholesterol 7α-hydroxylase, and sterol carrier protein-2 are important …

We investigated whether maternal over-nutrition during pregnancy and lactation affects the
offspring's lipid metabolism at weaning by assessing liver lipid metabolic gene expressions …

Due to the insufficient fetal cholesterol synthesis, maternal cholesterol transport through the
placenta becomes an important source of fetal cholesterol pool, which is essential for fetal …

Maternal hypercholesterolemia (MHC) during pregnancy is associated with the risk of
developing aortic lesions in fetuses. There is also a possibility of faster progression of …

Obesity in pregnancy is associated with increased fetal growth and adiposity, which, in part,
is determined by transplacental nutrient supply. Trophoblast uptake and intracellular …

Dyslipidemia is a characteristic of maternal obesity and previous studies have demonstrated
abnormalities in fatty acid oxidation and storage in term placentas. However, there is little …

OBJECTIVE This study addressed the hypothesis that placental endothelial lipase (EL)
expression is affected by pregnancies complicated by obesity and gestational diabetes …

OBJECTIVE: Changes in metabolic homeostasis in pregnant diabetic women are potential
determinants of increased adiposity of the fetus. The aim of this study was to characterize …

Lipids are crucial structural and bioactive components that sustain embryo, fetal and
placental development and growth. Intrauterine development can be disturbed by several …