Direct Comparison of the Effectiveness and Safety Among Direct Oral Anticoagulants and Warfarin in Japanese Patients: Nationwide Cohort Study in Japan

S Katayama, Y Aoki, A Akita, R Satake… - Clinical Pharmacology …, 2024 - Wiley Online Library
Direct oral anticoagulant drugs (DOACs) are available in addition to warfarin for the
treatment of patients with non‐valvular atrial fibrillation (NVAF). Anticoagulants are useful for …

Comparison of Efficacy and Safety of Direct Oral Anticoagulants and Warfarin between Patients in Asian and Non‐Asian Regions: A Systematic Review and Meta …

K Ambe, A Akita, J Wei, Y Yoshii… - Clinical …, 2023 - Wiley Online Library
Direct oral anticoagulants (DOACs) have increasingly replaced warfarin for treating patients
with non‐valvular atrial fibrillation (NVAF). DOACs have been demonstrated to be more …

Effectiveness and safety of reduced and standard daily doses of direct oral anticoagulants in patients with nonvalvular atrial fibrillation: A cohort study using national …

K Kubota, N Ooba - Clinical Epidemiology, 2022 - Taylor & Francis
Purpose To compare the effectiveness and safety of reduced or standard daily doses of
direct oral anticoagulants (DOACs) with warfarin in Japanese patients with nonvalvular atrial …

Dose of direct oral anticoagulants and adverse outcomes in Asia

J Ohno, Y Sotomi, A Hirata, Y Sakata… - The American Journal of …, 2021 - Elsevier
The present study aimed to assess the associations between dosing of DOACs and
outcomes in patients with non-valvular atrial fibrillation (NVAF). Direct oral anticoagulants …

Drug class, renal elimination, and outcomes of direct oral anticoagulants in Asian patients: a meta-analysis

KL Wang, CC Chiu, RP Giugliano, DSY Tan… - Journal of Stroke and …, 2018 - Elsevier
Background Direct oral anticoagulants (DOACs) have a better risk benefit profile in Asian
patients with atrial fibrillation (AF). Whether treatment effects could be modified by drug class …

Effectiveness and safety of four direct oral anticoagulants in Asian patients with nonvalvular atrial fibrillation

YH Chan, HF Lee, LC See, HT Tu, TF Chao, YH Yeh… - Chest, 2019 - Elsevier
Background Whether four direct oral anticoagulants (DOACs) are superior to warfarin in
Asian patients with nonvalvular atrial fibrillation (NVAF) remains unclear. Methods This …

Evaluation of the efficacy and safety of direct oral anticoagulants in Japanese patients—analysis of pharmaceuticals and medical devices agency data

Y Terayama - Journal of Stroke and Cerebrovascular Diseases, 2017 - Elsevier
Background Two forms of direct oral anticoagulant (DOAC) have recently been introduced:
direct thrombin inhibitors (DTI; eg, dabigatran) and factor Xa inhibitors (FXa; eg, rivaroxaban …

Comparison of the effectiveness and safety of direct oral anticoagulants: a nationwide propensity score–weighted study

AB Ingason, JP Hreinsson, AS Agustsson… - Blood …, 2023 - ashpublications.org
In the pivotal randomized controlled trials (RCTs) for patients with atrial fibrillation, direct oral
anticoagulants (DOACs) had similar or even superior efficacy and safety compared with …

Incidence of stroke, systemic embolism and bleeding events in patients without anticoagulation based on real-world data in Japan: a retrospective cohort study

K Tanizawa, Y Nishimura, S Sera, D Yaguchi… - BMJ open, 2022 - bmjopen.bmj.com
Objectives To examine the incidence of stroke or systemic embolic events (SSEs) and
bleeding events in untreated patients with non-valvular atrial fibrillation (NVAF) after …

Effectiveness and safety among direct oral anticoagulants in nonvalvular atrial fibrillation: A multi‐database cohort study with meta‐analysis

M Durand, ME Schnitzer, M Pang… - British Journal of …, 2021 - Wiley Online Library
Aims There are conflicting signals in the literature about comparative safety and
effectiveness of direct oral anticoagulants (DOACs) for nonvalvular atrial fibrillation (NVAF) …