Minireview: Glucocorticoids in autoimmunity: unexpected targets and mechanisms
JR Flammer, I Rogatsky - Molecular endocrinology, 2011 - academic.oup.com
For decades, natural and synthetic glucocorticoids (GC) have been among the most
commonly prescribed classes of immunomodulatory drugs. Their unsurpassed …
commonly prescribed classes of immunomodulatory drugs. Their unsurpassed …
The role of the glucocorticoid receptor in inflammation and immunity
U Baschant, J Tuckermann - The Journal of steroid biochemistry and …, 2010 - Elsevier
Glucocorticoids are potent immunosuppressive agents with complex actions on immune
cells evoking the following effects: inducing apoptosis, changing differentiation fate …
cells evoking the following effects: inducing apoptosis, changing differentiation fate …
Therapeutic mechanisms of glucocorticoids
J Vandewalle, A Luypaert, K De Bosscher… - Trends in Endocrinology & …, 2018 - cell.com
Glucocorticoids (GCs) have been used clinically for decades as potent anti-inflammatory
and immunosuppressive agents. Nevertheless, their use is severely hampered by the risk of …
and immunosuppressive agents. Nevertheless, their use is severely hampered by the risk of …
Immune regulation by glucocorticoids
DW Cain, JA Cidlowski - Nature Reviews Immunology, 2017 - nature.com
Endogenous glucocorticoids are crucial to various physiological processes, including
metabolism, development and inflammation. Since 1948, synthetic glucocorticoids have …
metabolism, development and inflammation. Since 1948, synthetic glucocorticoids have …
[HTML][HTML] Regulatory and mechanistic actions of glucocorticoids on T and inflammatory cells
AC Liberman, ML Budzinski, C Sokn… - Frontiers in …, 2018 - frontiersin.org
Glucocorticoids (GCs) play an important role in regulating the inflammatory and immune
response and have been used since decades to treat various inflammatory and autoimmune …
response and have been used since decades to treat various inflammatory and autoimmune …
[HTML][HTML] Glucocorticoids—all-rounders tackling the versatile players of the immune system
C Strehl, L Ehlers, T Gaber, F Buttgereit - Frontiers in immunology, 2019 - frontiersin.org
Glucocorticoids regulate fundamental processes of the human body and control cellular
functions such as cell metabolism, growth, differentiation, and apoptosis. Moreover …
functions such as cell metabolism, growth, differentiation, and apoptosis. Moreover …
Effects of glucocorticoids in the immune system
E Oppong, ACB Cato - Glucocorticoid signaling: from molecules to mice to …, 2015 - Springer
Glucocorticoids (GCs) are steroid hormones with widespread effects. They control
intermediate metabolism by stimulating gluconeogenesis in the liver, mobilize amino acids …
intermediate metabolism by stimulating gluconeogenesis in the liver, mobilize amino acids …
The kaleidoscope of glucorticoid effects on immune system
M Zen, M Canova, C Campana, S Bettio, L Nalotto… - Autoimmunity …, 2011 - Elsevier
Glucocorticoids (GCs) are potent anti-inflammatory and immunosuppressive agents which
exert multiple effects on immune cell functions. Although their use dates back 60years, their …
exert multiple effects on immune cell functions. Although their use dates back 60years, their …
[HTML][HTML] Glucocorticoids, sex hormones, and immunity
O Bereshchenko, S Bruscoli, C Riccardi - Frontiers in immunology, 2018 - frontiersin.org
Glucocorticoid hormones regulate essential body functions in mammals, control cell
metabolism, growth, differentiation, and apoptosis. Importantly, they are potent suppressors …
metabolism, growth, differentiation, and apoptosis. Importantly, they are potent suppressors …
Novel insights into mechanisms of glucocorticoid action and the development of new glucocorticoid receptor ligands
M Löwenberg, C Stahn, DW Hommes, F Buttgereit - Steroids, 2008 - Elsevier
Glucocorticoids (GCs) are potent anti-inflammatory and immunosuppressant agents.
Unfortunately, they also produce serious side effects that limit their usage. This discrepancy …
Unfortunately, they also produce serious side effects that limit their usage. This discrepancy …