Designing tuberculosis vaccine efficacy trials–lessons from recent studies
AM Ginsberg - Expert Review of Vaccines, 2019 - Taylor & Francis
Introduction: Tuberculosis (TB) is the leading infectious killer globally and new TB vaccines
will be crucial to ending the epidemic. Since the introduction in 1921 of the only currently …
will be crucial to ending the epidemic. Since the introduction in 1921 of the only currently …
Clinical trials of TB vaccines: harmonization and cooperation
H Mahomed, PB Fourie - Tuberculosis, 2012 - Elsevier
A new efficacious tuberculosis (TB) vaccine has the potential to dramatically assist control
efforts for the global TB epidemic. Good progress has been made with the clinical …
efforts for the global TB epidemic. Good progress has been made with the clinical …
[PDF][PDF] The Tuberculosis vaccine pipeline
C Wingfield, R Jefferys - Pipeline Report, 2012 - i-base.info
BY CLAIRE WINGFIELD AND RICHARD JEFFERYS he Bacille Calmette-Guérin (BCG)
vaccine provides protection from the most severe forms of pediatric tuberculosis (TB) …
vaccine provides protection from the most severe forms of pediatric tuberculosis (TB) …
Tuberculosis vaccine: time to look into future
S Chawla, D Garg, D Garg, RB Jain… - Human Vaccines & …, 2014 - Taylor & Francis
Global burden of tuberculosis is nearly 12 million. As per the WHO Global TB Report 2013,
there were an estimated 8.6 million incident cases of TB globally in 2012. Tuberculosis is an …
there were an estimated 8.6 million incident cases of TB globally in 2012. Tuberculosis is an …
Development of tuberculosis vaccines in clinical trials: Current status
P Méndez‐Samperio - Scandinavian journal of immunology, 2018 - Wiley Online Library
Tuberculosis (TB) is an important infectious disease worldwide. Currently, Bacillus Calmette‐
Guérin (BCG) remains the only TB vaccine licensed for human use. This TB vaccine is …
Guérin (BCG) remains the only TB vaccine licensed for human use. This TB vaccine is …
[HTML][HTML] The tuberculosis vaccines pipeline
M Frick - TAG Pipeline Report, 2013 - i-base.info
The last year in tuberculosis (TB) vaccine research has demonstrated how setbacks can
sometimes produce the potential for unexpected progress. Dominant hypotheses have …
sometimes produce the potential for unexpected progress. Dominant hypotheses have …
[HTML][HTML] Research and development of new tuberculosis vaccines: a review
LK Schrager, RC Harris, J Vekemans - F1000Research, 2018 - ncbi.nlm.nih.gov
Tuberculosis kills more people worldwide than any other single infectious disease agent, a
threat made more dire by the spread of drug-resistant strains of Mycobacterium tuberculosis …
threat made more dire by the spread of drug-resistant strains of Mycobacterium tuberculosis …
New tuberculosis vaccine development
CA Nacy, KA Sacksteder - Expert Opinion on Biological Therapy, 2002 - Taylor & Francis
Tuberculosis (TB) is a devastating disease that kills more than three million people each
year. Of these, 0.9 million are co-infected with HIV and numbers of infections and death …
year. Of these, 0.9 million are co-infected with HIV and numbers of infections and death …
[HTML][HTML] Status of vaccine research and development of vaccines for tuberculosis
TG Evans, L Schrager, J Thole - Vaccine, 2016 - Elsevier
TB is now the single pathogen that causes the greatest mortality in the world, at over 1.6
million deaths each year. The widely used the 90 year old BCG vaccine appears to have …
million deaths each year. The widely used the 90 year old BCG vaccine appears to have …
[HTML][HTML] End-point definition and trial design to advance tuberculosis vaccine development
AL Garcia-Basteiro, RG White, D Tait… - European respiratory …, 2022 - Eur Respiratory Soc
Tuberculosis (TB) remains a leading infectious cause of death worldwide and the
coronavirus disease 2019 pandemic has negatively impacted the global TB burden of …
coronavirus disease 2019 pandemic has negatively impacted the global TB burden of …