Cardiovascular disease in patients with chronic inflammation: mechanisms underlying premature cardiovascular events in rheumatologic conditions
A variety of systemic inflammatory rheumatic diseases associate with an increased risk of
atherosclerotic events and premature cardiovascular (CV) disease. Although this recognition …
atherosclerotic events and premature cardiovascular (CV) disease. Although this recognition …
Explaining how “high-grade” systemic inflammation accelerates vascular risk in rheumatoid arthritis
N Sattar, DW McCarey, H Capell, IB McInnes - Circulation, 2003 - Am Heart Assoc
There is intense interest in mechanisms whereby low-grade inflammation could interact with
conventional and novel vascular risk factors to promote the atheromatous lesion. Patients …
conventional and novel vascular risk factors to promote the atheromatous lesion. Patients …
Atherosclerosis and inflammation: insights from rheumatoid arthritis
Cardiovascular disease is a major health care problem and the most common cause of
death among individuals from developed nations. Our understanding of atherosclerosis has …
death among individuals from developed nations. Our understanding of atherosclerosis has …
Cardiovascular co-morbidity in rheumatic diseases
C Turesson, LTH Jacobsson… - Vascular health and risk …, 2008 - Taylor & Francis
Patients with rheumatic disorders have an increased risk of cardiovascular disease (CVD).
This excess co-morbidity is not fully explained by traditional risk factors. Disease severity is a …
This excess co-morbidity is not fully explained by traditional risk factors. Disease severity is a …
Rheumatoid arthritis a model of systemic inflammation driving atherosclerosis
Similarities between the inflammatory pathways in atherosclerosis and rheumatoid arthritis
(RA) are striking. Chronic systemic inflammation in RA patients leads to cardiovascular (CV) …
(RA) are striking. Chronic systemic inflammation in RA patients leads to cardiovascular (CV) …
The rationale for comparative studies of accelerated atherosclerosis in rheumatic diseases
A Yuri Gasparyan… - Current vascular …, 2010 - ingentaconnect.com
The inflammatory pathogenesis of atherosclerosis is now well-established, owing to in vitro
and in vivo studies and the application of high sensitivity assays for C-reactive protein (CRP) …
and in vivo studies and the application of high sensitivity assays for C-reactive protein (CRP) …
Atherosclerosis in rheumatoid arthritis: is it all about inflammation?
S Skeoch, IN Bruce - Nature Reviews Rheumatology, 2015 - nature.com
Rheumatoid arthritis (RA) has long been associated with increased cardiovascular risk, but
despite substantial improvements in disease management, mortality remains high …
despite substantial improvements in disease management, mortality remains high …
Rheumatoid arthritis and cardiovascular disease: the role of systemic inflammation and evolving strategies of prevention
MH Snow, TR Mikuls - Current opinion in rheumatology, 2005 - journals.lww.com
The pathogenesis of cardiovascular disease in rheumatoid arthritis is complex and involves
several intermediate factors, including dyslipidemia, elevations in serum homocysteine …
several intermediate factors, including dyslipidemia, elevations in serum homocysteine …
Cardiovascular risk in rheumatoid arthritis: recent advances in the understanding of the pivotal role of inflammation, risk predictors and the impact of treatment
Risk of cardiovascular (CV) disease is increased among RA patients. High inflammatory
burden associated with RA appears to be a key driver of the increased cardiovascular risk …
burden associated with RA appears to be a key driver of the increased cardiovascular risk …
Inflammation and atherosclerosis in rheumatoid arthritis
RJ Stevens, KMJ Douglas, AN Saratzis… - Expert reviews in …, 2005 - cambridge.org
Rheumatoid arthritis (RA) associates with increased cardiovascular mortality. This appears
to be predominantly due to ischaemic causes, such as myocardial infarction and congestive …
to be predominantly due to ischaemic causes, such as myocardial infarction and congestive …
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