The molecular basis of drug action is often not well understood. This is partly because the
very abundant and diverse information generated in the past decades on drugs is hidden in …

There are at least two good reasons for the on-going interest in drug–target interactions: first,
drug-effects can only be fully understood by considering a complex network of interactions to …

Regular monitoring of drug regulatory agency web sites and similar resources for
information on new drug approvals and changes to legal status of marketed drugs is …

DrugBank is a richly annotated resource that combines detailed drug data with
comprehensive drug target and drug action information. Since its first release in 2006 …

The efficacy and safety of drugs are widely known to be determined by their interactions with
multiple molecules of pharmacological importance, and it is therefore essential to …

Abstract DrugBank (http://www. drugbank. ca) is a richly annotated database of drug and
drug target information. It contains extensive data on the nomenclature, ontology, chemistry …

First released in 2006, DrugBank (https://go. drugbank. com) has grown to become the 'gold
standard'knowledge resource for drug, drug–target and related pharmaceutical information …

The procedure of drug approval is time-consuming, costly and risky. Accidental findings
regarding multi-specificity of approved drugs led to block-busters in new indication areas …

Bioinformatic analysis can not only accelerate drug target identification and drug candidate
screening and refinement, but also facilitate characterization of side effects and predict drug …

Identification of possible protein targets of small chemical molecules is an important step for
unravelling their underlying causes of actions at the molecular level. To this end, we …