Overlapping clinical and pathomechanistic features can complicate the diagnosis and
treatment of inflammatory skin diseases, including psoriasis and atopic dermatitis (AD) …

During the last decades, high-throughput assessment of gene expression in patient tissues
using microarray technology or RNA-Seq took center stage in clinical research. Insights into …

Whereas the cellular and molecular features of human inflammatory skin diseases are well
characterized, their tissue context and systemic impact remain poorly understood. We thus …

During the last decades, high-throughput assessment of gene expression in patient tissues
using microarray technology or RNA-Seq took center stage in clinical research. Insights into …

Inflammatory skin diseases are induced by disorders of the host defense system of the skin,
which is composed of a barrier, innate and acquired immunity, as well as the cutaneous …

Psoriasis is a chronic inflammatory skin disease, thought to be predominantly mediated by
TH 17 cells. Significance of other inflammatory pathways and the innate immune system is …

Psoriasis, which is one of the most common skin diseases, involves an array of complex
immune constituents including T cells, dendritic cells and monocytes. Particularly, the …

Keratinocytes are one of the primary cells affected by psoriasis inflammation. Our study
aimed to delve deeper into their morphology, transcriptome, and epigenome changes in …

Psoriasis is a common chronic inflammatory skin disease mediated by innate and adaptive
immune systems, characterized by abnormal proliferation and differentiation of epidermal …

Psoriasis is an immune-mediated inflammatory skin disease with a complex etiology
involving environmental and genetic factors. A better insight into related genomic alteration …