Lactose synthase (a complex of β1, 4-galactosyltransferase and α-lactalbumin) forms
lactose in the Golgi complex of mammary epithelial cells. To determine whether α …

Transgenic mice were produced to study the production of bovine α-LA in their milk. A 7.6-kb
fragment containing a bovine α-LA gene was purified and microinjected into pronuclear …

Lowering the lactose content of milk in vivo has two potential benefits: to develop milk
products for lactose intolerant people (Delmont, 1983) and to produce a more concentrated …

This study was performed to examine the effects of α-lactalbumin (a major whey protein in
mammals) overexpression on lactation in the pig and to test the ability of the bovine α …

High production of milk and its components are necessary to allow maximal growth of
developing pigs. In this study, transgenic pigs were produced containing the α-lactalbumin …

Abstract α-Lactalbumin, a modifier protein that changes the substrate specificity of
galactosyltransferase, to promote the synthesis of lactose, is found in the mammary glands …

The goal of this study was to determine whether the presence of the bovine alpha-
lactalbumin transgene in first-lactation gilts enhances lactational performance and litter …

Improvement of the nutritional value of cow milk with transgenic expression of recombinant
human α-lactalbumin (α-LA) has been previously attempted. However, the detailed …

alpha-Lactalbumin is an abundant milk-specific calcium metalloprotein which has an
evolutionary relationship to lysozyme. It modifies the substrate specificity of a Golgi …

Mice carrying either a deletion of the murine alpha-lactalbumin (alpha-lac) gene (null allele)
or its replacement by the human alpha-lac gene (humanized allele) have been generated by …