[HTML][HTML] An optimised monophasic faecal extraction method for LC-MS analysis and its application in gastrointestinal disease
PE Kelly, HJ Ng, G Farrell, S McKirdy, RK Russell… - Metabolites, 2022 - mdpi.com
Liquid chromatography coupled with mass spectrometry (LC-MS) metabolomic approaches
are widely used to investigate underlying pathogenesis of gastrointestinal disease and …
are widely used to investigate underlying pathogenesis of gastrointestinal disease and …
Validated high resolution mass spectrometry-based approach for metabolomic fingerprinting of the human gut phenotype
J Vanden Bussche, M Marzorati, D Laukens… - Analytical …, 2015 - ACS Publications
Fecal samples are an obvious choice for metabolomic approaches, since they can be
obtained noninvasively and allow one to study the interactions between the gut microbiota …
obtained noninvasively and allow one to study the interactions between the gut microbiota …
Metabolomic analysis—Addressing NMR and LC-MS related problems in human feces sample preparation
S Moosmang, M Pitscheider, S Sturm, C Seger… - Clinica Chimica …, 2019 - Elsevier
Metabolomics is a well-established field in fundamental clinical research with applications in
different human body fluids. However, metabolomic investigations in feces are currently an …
different human body fluids. However, metabolomic investigations in feces are currently an …
[HTML][HTML] High-throughput UHPLC-MS to screen metabolites in feces for gut metabolic health
Feces are the product of our diets and have been linked to diseases of the gut, including
Chron's disease and metabolic diseases such as diabetes. For screening metabolites in …
Chron's disease and metabolic diseases such as diabetes. For screening metabolites in …
[HTML][HTML] An LC-QToF MS based method for untargeted metabolomics of human fecal samples
K Cheng, C Brunius, R Fristedt, R Landberg - Metabolomics, 2020 - Springer
Introduction Consensus in sample preparation for untargeted human fecal metabolomics is
lacking. Objectives To obtain sample preparation with broad metabolite coverage for high …
lacking. Objectives To obtain sample preparation with broad metabolite coverage for high …
[HTML][HTML] Towards standards for human fecal sample preparation in targeted and untargeted lc-hrms studies
Gut microbiota and their metabolic products are increasingly being recognized as important
modulators of human health. The fecal metabolome provides a functional readout of the …
modulators of human health. The fecal metabolome provides a functional readout of the …
Sample preparation optimization in fecal metabolic profiling
Metabolomic analysis of feces can provide useful insight on the metabolic status, the
health/disease state of the human/animal and the symbiosis with the gut microbiome. As a …
health/disease state of the human/animal and the symbiosis with the gut microbiome. As a …
Human Faecal 1H NMR Metabolomics: Evaluation of Solvent and Sample Processing on Coverage and Reproducibility of Signature Metabolites
The human faecal metabolome is complex, but rich in information and allows investigation of
the host metabolism as a function of diet and health. The faecal metabolome is still much …
the host metabolism as a function of diet and health. The faecal metabolome is still much …
[PDF][PDF] Optimisation of sample preparation for direct SPME-GC-MS analysis of murine and human faecal volatile organic compounds for metabolomic studies
S Reade, A Mayor, R Aggio, T Khalid… - J Anal Bioanal …, 2014 - researchgate.net
The analysis of volatile organic compounds (VOCs) emitted from biological fluids such as
blood, urine, breath and faeces, has been receiving more attention from researchers and …
blood, urine, breath and faeces, has been receiving more attention from researchers and …
[HTML][HTML] Metabonomics of human fecal extracts characterize ulcerative colitis, Crohn's disease and healthy individuals
This study employs spectroscopy-based metabolic profiling of fecal extracts from healthy
subjects and patients with active or inactive ulcerative colitis (UC) and Crohn's disease (CD) …
subjects and patients with active or inactive ulcerative colitis (UC) and Crohn's disease (CD) …