Recent reports indicate that children receiving a fifth consecutive dose of DTPa vaccine
have a moderate likelihood of developing a large injection site reaction, the etiology of …

OBJECTIVE: To assess whether the risk of medically attended local reactions to the fifth
dose of the diphtheria and tetanus toxoids and acellular pertussis (DTaP) vaccine varies …

Objective. To facilitate future vaccine reaction data collection and analysis, we sought to
determine the minimum data set required to describe accurately and to compare common …

Background: Large injection site reactions commonly follow booster doses of diphtheria-
tetanus-acellular pertussis (DTaP) vaccines at 4–6 years of age. A vaccine with lower …

The objective of this study was to evaluate reactogenicity and immunogenicity of the recently
US-licensed Connaught/BIKEN (C/B) acellular DTP (ADTP) vaccine as a booster for children …

Background: Safety of a sixth consecutive dose of acellular pertussis vaccine in adolescents
was assessed in a 2-armed, randomized study. Methods: Adolescents who had received 5 …

Background. Acellular pertussis (aP)-containing vaccines cause fewer adverse events than
whole-cell versions for primary doses. Booster doses, however, may be followed by …

We performed a randomized, controlled clinical trial to characterize the evolution of the
adverse events associated with the fifth consecutive dose of an acellular pertussis vaccine …

Objective: To assess the reported rate of local reactions after administration of acellular
pertussis vaccine (DTPa) according to dose number and type of pertussis vaccine (whole …

Objective. To evaluate the relative frequency of adverse reactions after initial and
subsequent immunizations among infants receiving primary immunization with acellular …