Efficacy and safety of early switch to oral anticoagulation in acute intermediate-risk pulmonary embolism

FA Klok, G Toenges, S Barco… - European Heart …, 2021 - academic.oup.com
Background Guidelines recommend risk-adjusted management of pulmonary embolism
(PE). We investigated whether treatment of acute intermediate-risk PE with parenteral …

Early switch to oral anticoagulation in patients with acute intermediate-risk pulmonary embolism (PEITHO-2): a multinational, multicentre, single-arm, phase 4 trial

FA Klok, G Toenges, AC Mavromanoli… - The Lancet …, 2021 - thelancet.com
Background Current guidelines recommend a risk-adjusted treatment strategy for the
management of acute pulmonary embolism. This is a particular patient category for whom …

Dabigatran after short heparin anticoagulation for acute intermediate-risk pulmonary embolism: rationale and design of the single-arm PEITHO-2 study

FA Klok, W Ageno, S Barco, H Binder… - Thrombosis and …, 2017 - thieme-connect.com
Patients with intermediate-risk pulmonary embolism (PE) may, depending on the method
and cut-off values used for definition, account for up to 60% of all patients with PE and have …

Should oral anticoagulation be discontinued after 3 months in the setting of a first high-risk pulmonary embolism secondary to a major transient/reversible risk factor?

G Meyer, S Konstantinides - European Respiratory Journal, 2020 - Eur Respiratory Soc
We would like to thank H. Slabbynck and co-workers for their interest in the 2019 European
Society of Cardiology/European Respiratory Society guidelines on the diagnosis and …

Initial anticoagulation therapy with direct oral anticoagulants in patients with intermediate-high-risk pulmonary embolism: from the COMMAND VTE Registry-2

R Shigeno, K Kim, R Chatani, K Kaneda… - European Heart …, 2023 - academic.oup.com
Background Patients with intermediate-high-risk pulmonary embolism (PE) who have both
right ventricular dysfunction and elevated cardiac biomarkers are at a high risk of early …

Contemporary anticoagulant treatment strategies in patients with acute pulmonary embolism at different risk for death

C Becattini, G Agnelli, M Diamanti, AP Maggioni… - Vascular …, 2023 - Elsevier
Introduction Availability of new treatment strategies for patients with acute pulmonary
embolism (PE) have changed clinical practice with potential influence in short-term patients' …

[HTML][HTML] Early, real-world experience with direct oral anticoagulants in the treatment of intermediate-high risk acute pulmonary embolism

SM Santos, S Cunha, R Baptista, S Monteiro… - Revista Portuguesa de …, 2017 - Elsevier
Introduction Intermediate-high risk pulmonary embolism (IHR-PE) has a poor prognosis, but
is under-represented in trials of direct oral anticoagulants (DOACs) in venous …

Early prescription of direct oral anticoagulant for the treatment of intermediate-high risk pulmonary embolism: a multi-center, observational cohort study

R Chopard, M Badoz, C Eveno, F Ecarnot, N Falvo… - Thrombosis …, 2020 - Elsevier
Objectives The safety and efficacy of direct oral anticoagulants (DOACs) in intermediate-
high risk pulmonary embolism (PE) are unknown. The aims of the present study were to …

Clinical patterns and significance of non-compliance with guideline-recommended treatment of acute pulmonary embolism

L Cart, G Serzian, S Humbert, N Falvo… - Archives of …, 2020 - Elsevier
Background Evidence-based clinical practice guidelines define initial management of acute
pulmonary embolism (PE) according to risk stratification for early death. Aims The aims of …

Pulmonary embolism: future perspectives and ongoing trials

I Ahrens - European Heart Journal Acute Cardiovascular Care, 2021 - academic.oup.com
Stavros Konstantinides: Risk-adjusted treatment of PE has indeed been the focus of our
research for more than three decades, and in the 2019 ESC Guidelines we put a lot of effort …