Effect of clopidogrel on adhesion molecules, hemostasis, and fibrinolysis in coronary heart disease
T Walter, S Szabo, S Kazmaier… - Journal of …, 2008 - journals.lww.com
Background: The interaction among inflammation, Hemostasis, and fibrinolysis plays a
major role in the genesis of coronary artery disease (CAD). The aim of the study was to …
major role in the genesis of coronary artery disease (CAD). The aim of the study was to …
Effects of combined therapy with clopidogrel and acetylsalicylic acid on platelet glycoprotein expression and aggregation
G Dörr, G Schmidt, M Gräfe… - Journal of …, 2002 - journals.lww.com
This study aimed to compare the effects of clopidogrel, acetylsalicylic acid (ASA), and the
combination of both substances on platelet aggregation and expression of platelet …
combination of both substances on platelet aggregation and expression of platelet …
Antiplatelet effects of clopidogrel compared with aspirin after myocardial infarction: enhanced inhibitory effects of combination therapy
K Moshfegh, M Redondo, F Julmy… - Journal of the American …, 2000 - jacc.org
OBJECTIVES We sought to compare the inhibitory effects of the combination of two doses of
aspirin plus clopidogrel with either drug alone on platelet aggregation and activation …
aspirin plus clopidogrel with either drug alone on platelet aggregation and activation …
Soluble P-selectin level correlates with acetylsalicylic acid but not with clopidogrel response in patients with stable coronary artery disease after a percutaneous …
J Kaufmann, E Wellnhofer, K Kappert… - Coronary artery …, 2013 - journals.lww.com
Background Impaired response to dual antiplatelet therapy is associated with worse
cardiovascular outcome. Besides antiplatelet effects, there is evidence that both clopidogrel …
cardiovascular outcome. Besides antiplatelet effects, there is evidence that both clopidogrel …
Lack of evidence for pleiotropic effects of clopidogrel on endothelial function and inflammation in patients with stable coronary artery disease: results of the double …
MA Ostad, E Nick, V Paixao-Gatinho… - Clinical research in …, 2011 - Springer
Background Recently we have demonstrated a dose-dependent improvement of endothelial
function after administration of a single loading dose of clopidogrel in patients with coronary …
function after administration of a single loading dose of clopidogrel in patients with coronary …
Clopidogrel inhibits platelet aggregation in patients on aspirin with stable chronic angina pectoris
S Saha, M Berglund, C Sylvén, A Gordon… - International journal of …, 2008 - Elsevier
Ten patients with chronic stable angina pectoris and ten aged-matched healthy controls
were investigated. Aspirin was given as 160 mg/day and clopidogrel as 300 mg loading …
were investigated. Aspirin was given as 160 mg/day and clopidogrel as 300 mg loading …
Clopidogrel but not aspirin reduces P‐selectin expression and formation of platelet‐leukocyte aggregates in patients with atherosclerotic vascular disease
U Klinkhardt, R Bauersachs, J Adams… - Clinical …, 2003 - Wiley Online Library
Formation of platelet‐leukocyte aggregates via the CD62 ligand represents an important
mechanism by which leukocytes contribute to thrombotic events. In a cross‐sectional study …
mechanism by which leukocytes contribute to thrombotic events. In a cross‐sectional study …
No difference in the effects of clopidogrel and aspirin on inflammatory markers in patients with coronary heart disease
S Solheim, AA Pettersen, H Arnesen… - Thrombosis and …, 2006 - thieme-connect.com
Aspirin reduces several pro-inflammatory markers in patients with coronary heart disease
(CHD), while limited data exists with clopidogrel. The aim of the present substudy of ASCET …
(CHD), while limited data exists with clopidogrel. The aim of the present substudy of ASCET …
Effect of clopidogrel on the inflammatory progression of early atherosclerosis in rabbits model
M Li, Y Zhang, H Ren, Y Zhang, X Zhu - Atherosclerosis, 2007 - Elsevier
Atherosclerosis is an inflammatory response of the arterial wall to 'injury', which is
prominently driven by inflammatory factors. Clopidogrel reduces early atherosclerosis …
prominently driven by inflammatory factors. Clopidogrel reduces early atherosclerosis …
Clopidogrel significantly lowers the development of atherosclerosis in ApoE-deficient mice in vivo
C Heim, J Gebhardt, M Ramsperger-Gleixner, J Jacobi… - Heart and vessels, 2016 - Springer
The anti-platelet drug clopidogrel has been shown to modulate adhesion molecule and
cytokine expression, both playing an important role in the pathogenesis of atherosclerosis …
cytokine expression, both playing an important role in the pathogenesis of atherosclerosis …
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