Sperm DNA Fragmentation has been extensively studied for more than a decade. In the
1940s the uniqueness of the spermatozoa protein complex which stabilizes the DNA was …

The integrity of the paternal genome is of paramount importance in the initiation and
maintenance of a pregnancy in vivo and in vitro. The presence in the embryonic genome of …

Sperm DNA fragmentation is being increasingly recognized as an important cause of
infertility. We herein describe the Sperm Chromatin Dispersion (SCD) test, a novel assay for …

Objective To develop a method to select spermatozoa with low DNA fragmentation rates for
assisted reproduction technologies (ART). Design Multistep prospective cohort study …

We herein summarise the evidence concerning the impact of sperm DNA fragmentation in
various clinical infertility scenarios and the advances on sperm DNA fragmentation tests …

[Frontiers in Bioscience 11, 1491-1499, May 1, 2006] 1491 Origin and biological
significance of DNA fragmentation in human sperm Page 1 [Frontiers in Bioscience 11, 1491-1499 …

OBJECTIVE: To review the mechanisms responsible for DNA fragmentation in human
sperm, including those occurring during spermatogenesis and transport through the …

Spermatozoa have the task to deliver an intact paternal genome to the oocyte and to support
a successful embryo development. The high levels of sperm DNA fragmentation (sDF) found …

Sperm DNA damage has been connected, among other things, with an increased incidence
of miscarriage and enhanced risk of disease in the offspring. However, its occurrence is …

The present-day laboratory methods of sperm analysis are a poor predictor of reproductive
outcome, and for many years it has been clear that newer and better tests are required …