WASP family proteins: Molecular mechanisms and implications in human disease
Abstract Proteins of the Wiskott-Aldrich syndrome protein (WASP) family play a central role
in regulating actin cytoskeletal dynamics in a wide range of cellular processes. Genetic …
in regulating actin cytoskeletal dynamics in a wide range of cellular processes. Genetic …
Regulation of WASp by phosphorylation: Activation or other functions?
A Dovas, D Cox - Communicative & integrative biology, 2010 - Taylor & Francis
Wiskott-Aldrich Syndrome protein (WASp) is an actin nucleation-promoting factor that
regulates actin polymerisation via the Arp2/3 complex. Its mutation in human syndromes has …
regulates actin polymerisation via the Arp2/3 complex. Its mutation in human syndromes has …
Regulation of Wiskott–Aldrich syndrome protein and related molecules
E Caron - Current opinion in cell biology, 2002 - Elsevier
Wiskott–Aldrich syndrome protein (WASP), the gene mutated in the haematological disorder
Wiskott-Aldrich syndrome, is the founding member of a family of conserved cytoskeletal …
Wiskott-Aldrich syndrome, is the founding member of a family of conserved cytoskeletal …
Ubiquitylation-dependent negative regulation of WASp is essential for actin cytoskeleton dynamics
B Reicher, N Joseph, A David, MH Pauker… - … and cellular biology, 2012 - Taylor & Francis
The Wiskott-Aldrich syndrome protein (WASp) is a key regulator of actin dynamics during
cell motility and adhesion, and mutations in its gene are responsible for Wiskott-Aldrich …
cell motility and adhesion, and mutations in its gene are responsible for Wiskott-Aldrich …
Cellular functions of WASP family proteins at a glance
O Alekhina, E Burstein… - Journal of cell …, 2017 - journals.biologists.com
ABSTRACT Proteins of the Wiskott–Aldrich syndrome protein (WASP) family function as
nucleation-promoting factors for the ubiquitously expressed Arp2/3 complex, which drives …
nucleation-promoting factors for the ubiquitously expressed Arp2/3 complex, which drives …
Waltzing with WASP
N Ramesh, IM Antón, N Martı́nez-Quiles, RS Geha - Trends in cell biology, 1999 - cell.com
Wiskott–Aldrich syndrome (WAS) is an inherited immune deficiency that is marked by
eczema, bleeding and recurrent infections. The lymphocytes and platelets of WAS patients …
eczema, bleeding and recurrent infections. The lymphocytes and platelets of WAS patients …
Recent advances in the biology of WASP and WIP
N Ramesh, R Geha - Immunologic Research, 2009 - Springer
WASP, the product of the gene mutated in Wiskott–Aldrich syndrome, is expressed only in
hematopoietic cells and is the archetype of a family of proteins that include N-WASP and …
hematopoietic cells and is the archetype of a family of proteins that include N-WASP and …
Mechanisms of WASp-mediated hematologic and immunologic disease
The Wiskott-Aldrich syndrome protein (WASp) is a key regulator of actin polymerization in
hematopoietic cells. The dynamic nature of cytoskeletal changes during a variety of cellular …
hematopoietic cells. The dynamic nature of cytoskeletal changes during a variety of cellular …
The Wiskott–Aldrich syndrome protein: forging the link between actin and cell activation
K Badour, J Zhang, KA Siminovitch - Immunological reviews, 2003 - Wiley Online Library
The Wiskott–Aldrich syndrome protein (WASp) has emerged as a central player in the
regulation of actin remodeling in T cells. The unique domain structure of WASp and other …
regulation of actin remodeling in T cells. The unique domain structure of WASp and other …
Physical mechanisms of signal integration by WASP family proteins
SB Padrick, MK Rosen - Annual review of biochemistry, 2010 - annualreviews.org
The proteins of the Wiskott-Aldrich syndrome protein (WASP) family are activators of the
ubiquitous actin nucleation factor, the Arp2/3 complex. WASP family proteins contain a C …
ubiquitous actin nucleation factor, the Arp2/3 complex. WASP family proteins contain a C …