After compaction, the preimplantation mouse embryo switches to a glucose-based
metabolism, whereas for the 2-to 4-cell stage embryo, glucose can be inhibitory. In this …

Mouse preimplantation embryos consume pyruvate preferentially during the early
developmental stages, before glucose becomes the predominant energy substrate in the …

Relative preferences of energy substrates (glucose, pyruvate, and lactate) for in vitro
development of hamster 8-cell embryos were investigated. Using protein-free modified …

Although human embryos will develop in vitro for six days or more, little is known about the
effects of the primary nutrients, pyruvate and glucose, on development. Because the nutrient …

The glucose metabolism and embryonic development of rat embryos during organogenesis
was studied using embryo culture. Glucose uptake and embryonic growth and differentiation …

A high‐glucose concentration in the reproductive tract during early development may result
in aberrant embryo or fetal development, with effects that could have a greater impact on …

Embryos of certain inbred mouse strains, and their F1 hybrids, are able to develop from the 1-
cell to blastocyst stage in simple chemically defined media containing lactate (L), pyruvate …

One-cell CF-1× B 6 SJLF 1/J embryos, which usually exhibit a 2-cell block to development in
vitro, have been cultured to the blastocyst stage using CZB medium and a glucose washing …

Rat one-cell embryos recovered from naturally mated females were cultured in modified
hamster embryo culture medium 1 without amino acids. In the presence of 0.4 mmol …

Preliminary observations showed that one-cell embryos from random-bred MF1 mice avoid
cleavage arrest at the two-cell stage ('in vitro two-cell block') when cultured in modified M16 …