An efficient one‐step radiosynthesis of [18F]FE‐PE2I, a PET radioligand for imaging of dopamine transporters
V Stepanov, R Krasikova, L Raus… - Journal of Labelled …, 2012 - Wiley Online Library
The aim of this study was to develop a direct fluorination method for the preparation of [18F]‐
(E)‐N‐(3‐iodoprop‐2‐enyl)‐2β‐carbofluoroethoxy‐3β‐(4′‐methyl‐phenyl) nortropane …
(E)‐N‐(3‐iodoprop‐2‐enyl)‐2β‐carbofluoroethoxy‐3β‐(4′‐methyl‐phenyl) nortropane …
Simplified synthesis of N‐(3‐[18F]fluoropropyl)‐2β‐carbomethoxy‐3β‐(4‐fluorophenyl)nortropane ([18F]β‐CFT‐FP) using [18F]fluoropropyl tosylate as the …
T Koivula, O Perhola, EL Kämäräinen… - Journal of Labelled …, 2005 - Wiley Online Library
A synthesis method has been developed for the labelling of N‐(3‐[18F] fluoropropyl)‐2β‐
carbomethoxy‐3β‐(4‐fluorophenyl) nortropane ([18F] β‐CFT‐FP), a potential radioligand for …
carbomethoxy‐3β‐(4‐fluorophenyl) nortropane ([18F] β‐CFT‐FP), a potential radioligand for …
Synthesis and radiopharmacological characterization of 2β-carbo-2′-[18F] fluoroethoxy-3β-(4-bromo-phenyl) tropane ([18F] MCL-322) as a PET radiotracer for …
The fluoroalkyl-containing tropane derivative 2β-carbo-2′-fluoroethoxy-3β-(4-bromo-
phenyl) tropane (MCL-322) is a highly potent and moderately selective ligand for the …
phenyl) tropane (MCL-322) is a highly potent and moderately selective ligand for the …
One‐step radiosynthesis of [18F]LBT‐999: a selective radioligand for the visualization of the dopamine transporter with PET
F Dollé, J Helfenbein, F Hinnen, S Mavel… - Journal of Labelled …, 2007 - Wiley Online Library
Abstract LBT‐999 (8‐((E)‐4‐fluoro‐but‐2‐enyl)‐3‐beta‐p‐tolyl‐8‐aza‐bicyclo [3.2. 1]
octane‐2‐beta‐carboxylicacid methyl ester) is a recently developed cocaine derivative …
octane‐2‐beta‐carboxylicacid methyl ester) is a recently developed cocaine derivative …
Synthesis of (E)‐N‐(3‐bromoprop‐2‐enyl)‐2β‐carbomethoxy‐3β‐(4′‐tolyl) nortropane (PE2Br) and radiolabelling of [76Br]PE2Br: a potential ligand for exploration …
J Helfenbein, P Emond, C Loc'h… - Journal of Labelled …, 1999 - Wiley Online Library
In order to study the dopamine transporter by PET, we prepared (E)‐N‐(3‐bromoprop‐2‐
enyl)‐2β‐carbomethoxy‐3β‐(4′‐tolyl) nortropane (PE2Br) and its radiobrominated …
enyl)‐2β‐carbomethoxy‐3β‐(4′‐tolyl) nortropane (PE2Br) and its radiobrominated …
Preparation of [18F]β‐CFT‐FP and [11C]β‐CFT‐FP, selective radioligands for visualisation of the dopamine transporter using positron emission tomography (PET)
EL Kämäräinen, T Kyllönen… - Journal of Labelled …, 2000 - Wiley Online Library
In this study the N‐fluoropropyl analogue of the cocaine congener β‐CFT (I), N‐(3‐
fluoropropyl)‐2β‐carbomethoxy‐3β‐(4‐fluorophenyl) nortropane (β‐CFT‐FP, III), was …
fluoropropyl)‐2β‐carbomethoxy‐3β‐(4‐fluorophenyl) nortropane (β‐CFT‐FP, III), was …
Radiosynthesis of [18F]LBT‐999, a selective radioligand for the visualization of the dopamine transporter with PET
F Dollé, F Hinnen, P Emond, S Mavel… - Journal of Labelled …, 2006 - Wiley Online Library
Abstract LBT‐999 (8‐((E)‐4‐fluoro‐but‐2‐enyl)‐3β‐p‐tolyl‐8‐aza‐bicyclo [3.2. 1] octane‐2β‐
carboxylic acid methyl ester) is a cocaine derivative belonging to a new generation of highly …
carboxylic acid methyl ester) is a cocaine derivative belonging to a new generation of highly …
[HTML][HTML] Fully Automated GMP-Compliant Synthesis of [18F]FE-PE2I
K Bratteby, CL Denholt, S Lehel, IN Petersen… - Pharmaceuticals, 2021 - mdpi.com
In the struggle to understand and accurately diagnose Parkinson′ s disease,
radiopharmaceuticals and medical imaging techniques have played a major role. By being …
radiopharmaceuticals and medical imaging techniques have played a major role. By being …
Whole-body biodistribution and dosimetry of the dopamine transporter radioligand 18F-FE-PE2I in human subjects
H Lizana, L Johansson, J Axelsson… - Journal of Nuclear …, 2018 - Soc Nuclear Med
18F-(E)-N-(3-iodoprop-2-enyl)-2β-carbofluoroethoxy-3β-(4′-methyl-phenyl) nortropane
(18F-FE-PE2I) was recently developed and has shown adequate affinity and high selectivity …
(18F-FE-PE2I) was recently developed and has shown adequate affinity and high selectivity …
Quantification of dopamine transporter in human brain using PET with 18F-FE-PE2I
18F-(E)-N-(3-iodoprop-2 E-enyl)-2β-carbofluoroethoxy-3β-(4-methylphenyl) nortropane (18F-
FE-PE2I) is a new PET radioligand with a high affinity and selectivity for the dopamine …
FE-PE2I) is a new PET radioligand with a high affinity and selectivity for the dopamine …
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