Immunotherapies have been transformative in many areas, including cancer treatments,
allergies, and autoimmune diseases. However, significant challenges persist in extending …

Therapies modulating the immune system offer the prospect of treating a wide range of
conditions including infectious diseases, cancer and autoimmunity. Biomaterials can …

Autoimmunity and allergies affect a large number of people across the globe. Current
approaches to these diseases target cell types and pathways that drive disease, but these …

Highlights•Biomaterials can potentially improve the safety and efficacy of cancer
immunotherapy.•Biomaterials scaffolds can program immune cell function in peripheral …

The prevalence of immune-mediated disorders, including autoimmune conditions and
allergies, is steadily increasing. However, current therapeutic approaches are often non …

Strategies to enhance, suppress, or qualitatively shape the immune response are of
importance for diverse biomedical applications, such as the development of new vaccines …

During autoimmunity or organ transplant rejection, the immune system attacks host or
transplanted tissue, causing debilitating inflammation for millions of patients. There is no …

Immunotherapies are an evolving treatment paradigm for addressing cancer, autoimmunity,
and infection. While exciting, most of the existing therapies are limited by their specificity─ …

Modulation of the immune system is an important therapeutic strategy in a wide range of
diseases, and is fundamental to the development of vaccines. However, optimally safe and …

Inflammation is a crucial part of wound healing and pathogen clearance. However, it can
also play a role in exacerbating chronic diseases and cancer progression when not …