Clinical and chemical assessment of thyroid function during therapy with amiodarone

JA Amico, V Richardson, B Alpert… - Archives of Internal …, 1984 - jamanetwork.com
• Clinical and chemical variables of thyroid function were studied in 26 patients with
symptomatic ventricular tachyarrhythmias before and during long-term oral treatment with …

The effects of amiodarone on thyroid function

NS Jaggarao, J Sheldon, EN Grundy… - Postgraduate …, 1982 - academic.oup.com
The effects of amiodarone on thyroid function tests in 100 patients treated for 6 weeks to 8
years are reported. One patient became thyrotoxic and 10 developed latent or overt …

Effect of long-term amiodarone therapy on thyroid hormone levels and thyroid function

GD Borowski, CD Garofano, LI Rose… - The American journal of …, 1985 - Elsevier
Both hyperthyroidism and hypothyroidism have been noted to occur in some patients treated
with amiodarone for cardiac arrhythmias. To determine the frequency of the development of …

Amiodarone and thyroid dysfunction.

H Padmanabhan - Southern medical journal, 2010 - europepmc.org
Amiodarone is a potent antiarrhythmic drug associated with thyroid dysfunction. Its high
iodine content causes inhibition of 5'-deiodinase activity. Most patients remain euthyroid …

Effects of amiodarone on thyroid function in patients with ischaemic heart disease.

DA Pritchard, BN Singh, PJ Hurley - Heart, 1975 - heart.bmj.com
Thyroid function was evaluated clinically and biochemically in 12 patients with ischaemic
heart disease receiving 200 mg oral amiodarone three times daily for periods up to 6 weeks …

Amiodarone, thyroid hormone indexes, and altered thyroid function: long-term serial effects in patients with cardiac arrhythmias

K Nademanee, BN Singh, B Callahan… - The American journal of …, 1986 - Elsevier
Amiodarone, a drug that has electrophysiologic actions resembling those of hypothyroidism,
increases serum levels of T 4 and reverse T 3 (rT 3) and decreases T 3. The drug's long-term …

Amiodarone and the thyroid gland. A review.

MH Jonckheer - Acta cardiologica, 1981 - europepmc.org
The author presents his experience with the thyroid complications of amiodarone therapy:
exceptional but sometimes serious conditions. Both, hypo-and hyperthyroidism can occur …

Amiodarone and the thyroid.

RL Kennedy, H Griffiths, TA Gray - Clinical chemistry, 1989 - academic.oup.com
An antiarrhythmic drug, amiodarone, contains 37% iodine by weight and is structurally
similar to the thyroid hormones. The drug inhibits hepatic 5'-deiodinase, resulting in …

[PDF][PDF] Amiodarone and the thyroid

MD Gammage, JA Franklyn - QJM: An International Journal of …, 1987 - academia.edu
Amiodarone, an iodinated benzofuran derivative, was introduced in the 1960s as an
antianginal agent with coronary vasodilator properties. Later description of its antiaiThythmic …

Thyrotoxicosis followed by hypothyroidism in patients treated with amiodarone: a possible consequence of a destructive process in the thyroid

E Roti, R Minelli, E Gardini, L Bianconi… - Archives of Internal …, 1993 - jamanetwork.com
Amiodarone is an iodine-rich drug used in the treatment of resistant cardiac arrhythmias.
Amiodarone-induced thyrotoxicosis (AIT) is well recognized and is generally believed to be …