Protein-protein interaction and pathway analyses of top schizophrenia genes reveal schizophrenia susceptibility genes converge on common molecular networks and …
Recent genome-wide association studies have identified many promising schizophrenia
candidate genes and demonstrated that common polygenic variation contributes to …
candidate genes and demonstrated that common polygenic variation contributes to …
[HTML][HTML] Common and rare genetic risk factors converge in protein interaction networks underlying schizophrenia
Hundreds of genomic loci have been identified with the recent advances of schizophrenia in
genome-wide association studies (GWAS) and sequencing studies. However, the functional …
genome-wide association studies (GWAS) and sequencing studies. However, the functional …
Systems-level analysis of risk genes reveals the modular nature of schizophrenia
Schizophrenia (SCZ) is a complex mental disorder with high heritability. Genetic studies
(especially recent genome-wide association studies) have identified many risk genes for …
(especially recent genome-wide association studies) have identified many risk genes for …
[HTML][HTML] Schizophrenia interactome with 504 novel protein–protein interactions
Genome-wide association studies of schizophrenia (GWAS) have revealed the role of rare
and common genetic variants, but the functional effects of the risk variants remain to be …
and common genetic variants, but the functional effects of the risk variants remain to be …
[HTML][HTML] An integrated genomic analysis of gene-function correlation on schizophrenia susceptibility genes
TT Chu, Y Liu - Journal of human genetics, 2010 - nature.com
Schizophrenia is a highly complex inheritable disease characterized by numerous genetic
susceptibility elements, each contributing a modest increase in risk for the disease. Although …
susceptibility elements, each contributing a modest increase in risk for the disease. Although …
[HTML][HTML] Limited association between schizophrenia genetic risk factors and transcriptomic features
AW Yu, JD Peery, H Won - Genes, 2021 - mdpi.com
Schizophrenia is a polygenic disorder with many genomic regions contributing to
schizophrenia risk. The majority of genetic variants associated with schizophrenia lie in the …
schizophrenia risk. The majority of genetic variants associated with schizophrenia lie in the …
Integrated post-GWAS analysis sheds new light on the disease mechanisms of schizophrenia
Schizophrenia is a severe mental disorder with a large genetic component. Recent genome-
wide association studies (GWAS) have identified many schizophrenia-associated common …
wide association studies (GWAS) have identified many schizophrenia-associated common …
[PDF][PDF] Phenotypic landscape of schizophrenia-associated genes defines candidates and their shared functions
Genomic studies have identified hundreds of candidate genes near loci associated with risk
for schizophrenia. To define candidates and their functions, we mutated zebrafish orthologs …
for schizophrenia. To define candidates and their functions, we mutated zebrafish orthologs …
Systematic prioritization and integrative analysis of copy number variations in schizophrenia reveal key schizophrenia susceptibility genes
Schizophrenia is a common mental disorder with high heritability and strong genetic
heterogeneity. Common disease-common variants hypothesis predicts that schizophrenia is …
heterogeneity. Common disease-common variants hypothesis predicts that schizophrenia is …
[HTML][HTML] Pairwise common variant meta-analyses of schizophrenia with other psychiatric disorders reveals shared and distinct gene and gene-set associations
The complex aetiology of schizophrenia is postulated to share components with other
psychiatric disorders. We investigated pleiotropy amongst the common variant genomics of …
psychiatric disorders. We investigated pleiotropy amongst the common variant genomics of …