[HTML][HTML] A 3-miRNA signature predicts prognosis of pediatric and adolescent cytogenetically normal acute myeloid leukemia

R Zhu, W Zhao, F Fan, L Tang, J Liu, T Luo, J Deng… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Acute myeloid leukemia is a hematologic malignancy with significant molecular
heterogeneity. MicroRNAs have important biological functions and play critical roles in …

A 4‐microRNA signature for survival prognosis in pediatric and adolescent acute myeloid leukemia

R Zhu, W Lin, W Zhao, F Fan, L Tang… - Journal of cellular …, 2019 - Wiley Online Library
Acute myeloid leukemia (AML) is a hematologic malignancy with significant molecular
heterogeneity. MicroRNAs (miRNAs) play a critical role in AML diagnosis, pathogenesis …

MiRNA expression as outcome predictor in pediatric AML: systematic evaluation of a new model

I Ellson, J Martorell-Marugán, P Carmona-Sáez… - NPJ Genomic …, 2024 - nature.com
Accurately predicting patient outcomes is essential for optimizing treatment and improving
outcomes in pediatric acute myeloid leukemia (AML). In recent years, microRNAs have …

Selection of three miRNA signatures with prognostic value in non-M3 acute myeloid leukemia

Y Xue, Y Ge, M Kang, C Wu, Y Wang, L Rong, Y Fang - BMC cancer, 2019 - Springer
Background MiRNAs that are potential biomarkers for predicting prognosis for acute myeloid
leukemia (AML) have been identified. However, comprehensive analyses investigating the …

MicroRNA expression-based model indicates event-free survival in pediatric acute myeloid leukemia

EL Lim, DL Trinh, RE Ries, J Wang… - Journal of Clinical …, 2017 - ascopubs.org
Purpose Children with acute myeloid leukemia (AML) whose disease is refractory to
standard induction chemotherapy therapy or who experience relapse after initial response …

MicroRNA patterns associated with clinical prognostic parameters and CNS relapse prediction in pediatric acute leukemia

H Zhang, XQ Luo, P Zhang, LB Huang, YS Zheng… - PloS one, 2009 - journals.plos.org
Background Recent reports have indicated that microRNAs (miRNAs) play a critical role in
malignancies, and regulations in the progress of adult leukemia. The role of miRNAs in …

A 3-microRNA scoring system for prognostication in de novo acute myeloid leukemia patients

MK Chuang, YC Chiu, WC Chou, HA Hou, EY Chuang… - Leukemia, 2015 - nature.com
As a highly heterogeneous disease, acute myeloid leukemia (AML) needs fine risk
stratification to get an optimal outcome of patients. MicroRNAs have florid biological …

Screening of prognostic risk microRNAs for acute myeloid leukemia

HY Gao, W Wang, XG Luo, YF Jiang, X He, P Xu… - …, 2018 - Taylor & Francis
Objectives This study aimed to investigate the risk miRNAs (microRNAs) for AML (acute
myeloid leukemia) prognosis and related regulatory mechanisms. Methods MiRNA and …

miR-370 is better than miR-375 as a non-invasive diagnostic biomarker for pediatric acute myeloid leukemia patients

MM Ali, RH Mohamed, AA Sayed, S Ahmed… - Cancer …, 2022 - content.iospress.com
BACKGROUND: Acute myeloid leukemia (AML) is characterized by heterogeneity in
phenotypic, genotypic, and clinical traits. miRNAs play an important role in pathogenesis …

[HTML][HTML] Classification of pediatric acute myeloid leukemia based on miRNA expression profiles

A Obulkasim, JE Katsman-Kuipers, L Verboon… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Pediatric acute myeloid leukemia (AML) is a heterogeneous disease with respect to biology
as well as outcome. In this study, we investigated whether known biological subgroups of …