Five 2-hydroxy-3-substituted-aminomethyl naphthoquinones, nine 1, 2, 3-triazolic para-
naphthoquinones, five nor-β-lapachone-based 1, 2, 3-triazoles, and several other …

In continuing our screening program of naphthoquinone activity against Trypanosoma cruzi,
the aetiological agent of Chagas' disease, new β-lapachone-based 1, 2, 3-triazoles, 3 …

In our continued search for novel trypanocidal compounds, twenty-six derivatives of para-
and ortho-naphthoquinones coupled to 1, 2, 3-triazoles were synthesized. These …

The importance of American trypanosomiasis (Chagas' disease) in human pathology is
widely known. The prognosis of this disease is poor and the choice of effective medicines …

New naphthoquinone derivatives were synthesized and assayed against bloodstream
trypomastigote forms of Trypanosoma cruzi, the etiological agent of Chagas' disease. The …

[1, 2, 3]-Triazole derivatives of nor-β-lapachone were synthesized and assayed against the
infective bloodstream trypomastigote form of Trypanosoma cruzi, the etiological agent of …

The discovery and development of essential drugs for Chagas disease is a major concern
worldwide. New substituted 1, 4-naphthoquinones were synthesized and tested against the …

Four new naphthofuranquinones, obtained from 2-hydroxy-3-allyl-naphthoquinone (1) and
nor-lapachol (2), have their structures established by physical and X-ray analysis and their …

The available chemotherapy for Chagas disease, caused by Trypanosoma cruzi, is
unsatisfactory; therefore, there is an intense effort to find new drugs for the treatment of this …

In the search for new therapeutic alternatives for Chagas disease, a series of six aryloxy-
naphthoquinone derivatives were synthesized and evaluated in vitro against Trypanosoma …