Oxygen supplementation supports energy production during hypothermic machine perfusion in a model of donation after circulatory death donors
SA Hosgood, ML Nicholson - Transplantation, 2019 - journals.lww.com
Organ preservation has historically relied on the concept that by reducing the temperature to
4 C, cellular metabolism is reduced to approximately 10% of normal. 1 Therefore, it is …
4 C, cellular metabolism is reduced to approximately 10% of normal. 1 Therefore, it is …
Oxygenated versus standard cold perfusion preservation in kidney transplantation (COMPARE): a randomised, double-blind, paired, phase 3 trial
I Jochmans, A Brat, L Davies, HS Hofker… - The Lancet, 2020 - thelancet.com
Background Deceased donor kidneys are preserved in cold hypoxic conditions. Providing
oxygen during preservation might improve post-transplant outcomes, particularly for kidneys …
oxygen during preservation might improve post-transplant outcomes, particularly for kidneys …
Oxygenated end-hypothermic machine perfusion in expanded criteria donor kidney transplant: a randomized clinical trial
P Husen, C Boffa, I Jochmans, C Krikke, L Davies… - JAMA …, 2021 - jamanetwork.com
Importance Continuous hypothermic machine perfusion during organ preservation has a
beneficial effect on graft function and survival in kidney transplant when compared with static …
beneficial effect on graft function and survival in kidney transplant when compared with static …
Effects of oxygen during long-term hypothermic machine perfusion in a porcine model of kidney donation after circulatory death
Background. Hypothermic machine perfusion (HMP) has become standard care in many
center's to preserve kidneys donated after circulatory death (DCD). Despite a significant …
center's to preserve kidneys donated after circulatory death (DCD). Despite a significant …
Oxygenated hypothermic machine perfusion of kidneys donated after circulatory death: an international randomised controlled trial
I Jochmans, HS Hofker, L Davies… - 26th BTS Annual …, 2019 - dial.uclouvain.be
METHODS: An international, double-blinded, randomised, paired trial investigated the effect
of oxygenated (HMPO) vs non-oxygenated hypothermic machine perfusion (HMP) on 1y …
of oxygenated (HMPO) vs non-oxygenated hypothermic machine perfusion (HMP) on 1y …
Role of oxygenation in hypothermic machine perfusion of kidneys from heart beating donors
A Gallinat, A Paul, P Efferz, B Lüer, S Swoboda… - …, 2012 - journals.lww.com
Dynamic preservation of organ grafts by hypothermic machine perfusion (HMP) has
regained broader interest to provide better outcome after transplantation. One pivotal aspect …
regained broader interest to provide better outcome after transplantation. One pivotal aspect …
Hypothermic machine perfusion as a national standard preservation method for deceased donor kidneys
A Brat, KM de Vries, EWE van Heurn… - …, 2022 - journals.lww.com
Background. Recently, continuous nonoxygenated hypothermic machine perfusion (HMP)
has been implemented as standard preservation method for deceased donor kidneys in the …
has been implemented as standard preservation method for deceased donor kidneys in the …
[引用][C] Hypothermic oxygenated machine perfusion—Preliminary experience with end‐ischemic reconditioning of marginal kidney allografts
FA Meister, Z Czigany, J Bednarsch… - Clinical …, 2019 - Wiley Online Library
Dear editor, In the face of critical organ shortage, several machine perfusion (MP) strategies
have been developed aiming at reconditioning poor‐quality extended criteria donor (ECD) …
have been developed aiming at reconditioning poor‐quality extended criteria donor (ECD) …
The effects of oxygenation on ex vivo kidneys undergoing hypothermic machine perfusion
Background Supplemental oxygenation of the standard hypothermic machine perfusion
(HMP) circuit has the potential to invoke favorable changes in metabolism, optimizing …
(HMP) circuit has the potential to invoke favorable changes in metabolism, optimizing …
Influence of oxygen concentration during hypothermic machine perfusion on porcine kidneys from donation after circulatory death
DP Hoyer, A Gallinat, S Swoboda… - …, 2014 - journals.lww.com
Background Hypothermic machine perfusion (HMP) for preservation led to compelling
success for outcomes of renal transplantation. Application of different concentrations of …
success for outcomes of renal transplantation. Application of different concentrations of …