Abstract β-lactam resistance in bacteria is primarily mediated through the production of β-
lactamases. Among the several strategies explored to mitigate the issue of β-lactam …

In the antibacterial arsenal, β-lactams have held a prominent position, but increasing
resistance due to unauthorized use and genetic factors requires new strategies. Combining …

The β-lactamase of Pseudomonas aeruginosa is known to degrade β-lactam antibiotics
such as penicillins, cephalosporins, monobactams, and carbapenems. With the discovery of …

Introduction Antibacterial drugs have been widely used for the past century to treat diseases,
but their efficacy has been limited by multi-resistant pathogens, particularly those that utilize …

Extended-spectrum beta-lactamase (ESBL) producing Enterobacteriaceae infection is a
serious global threat. ESBLs target 3rd generation cephalosporin antibiotics, the most …

Drug resistance is an unsolved and major concern in the bacterial infection. Continuous
development of drug-resistance to the antibiotics exponentially rises the danger of bacterial …

Introduction This study aimed to evaluate new Staphylococcus aureus β-lactamase
inhibitors from medicinal plants Rosmarinus officinalis, Ocimum basilicum, Eucalyptus …

Antimicrobial resistance (AMR) threatens millions of people around the world and has been
declared a global risk by the World Economic Forum. One of the important AMR …

Background: Staphylococcus aureus (S. aureus) is a Gram-positive bacterium causing a
wide range of human infections, leading to life-threatening invasive disorders …

Abstract β-Lactamases are enzymes that catalyze the hydrolysis of the β-lactam ring,
resulting in loss of function in β-lactam antibiotics. In this report, the inhibition of β-lactamase …