Cognitive flexibility, the ability to alter strategy according to changing stimulus-response-
reward relationships, is critical for updating learned behavior. Attentional set-shifting, a test …

Cognitive flexibility is fundamental to adaptive intelligent behavior. Prefrontal cortex has long
been associated with flexible cognitive function, but the neurophysiological principles that …

The human ability to flexibly alternate between tasks represents a central component of
cognitive control. Neuroimaging studies have linked task switching with a diverse set of …

Interactions between the prefrontal cortex (PFC) and mediodorsal thalamus are critical for
cognitive flexibility, yet the underlying computations are unknown. To investigate …

The prefrontal cortex (PFC) is thought to play a critical role in behavioral flexibility by
monitoring action–outcome contingencies. How PFC ensembles represent shifts in behavior …

Prefrontal cortex (PFC) supports flexible behavior by mediating cognitive control, though the
elemental forms of control supported by PFC remain a central debate. Dorsolateral PFC …

Behavioral flexibility is the hallmark of goal-directed behavior. Whereas a great deal is
known about the neural substrates of behavioral adjustment when it is explicitly cued by …

The human prefrontal cortex (PFC) constitutes the structural basis underlying flexible
cognitive control, where mixed-selective neural populations encode multiple task features to …

The pFC is critical for cognitive flexibility (ie, our ability to flexibly adjust behavior to changing
environmental demands), but also for cognitive stability (ie, our ability to follow behavioral …

Human cognitive control is uniquely flexible and has been shown to depend on prefrontal
cortex (PFC). But exactly how the biological mechanisms of the PFC support flexible …