Adenosine receptor signaling plays important roles in normal physiology, but is also known
to modulate the development or progression of several different diseases. The design of …

Adenosine receptors (ARs) are widely acknowledged pharmacological targets yet are still
underutilized in clinical practice. Their ubiquitous distribution in almost all cells and tissues …

Adenosine receptors are major targets of caffeine, the most commonly consumed drug in the
world. There is growing evidence that they could also be promising therapeutic targets in a …

Adenosine is an endogenous nucleoside that regulates many physiological and
pathological processes. It is derived from either the intracellular or extracellular …

Adenosine is involved in a range of physiological and pathological effects through
membrane-bound receptors linked to G proteins. There are four subtypes of adenosine …

Our previous International Union of Basic and Clinical Pharmacology report on the
nomenclature and classification of adenosine receptors (2011) contained a number of …

Adenosine is a ubiquitous endogenous autacoid whose effects are triggered through the
enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Due to the rapid …

Adenosine, beside its role in the intermediate metabolism, mediates its physiological
functions by interacting with four receptor subtypes named A1, A2A, A2B and A3. All these …

Introduction: The adenosine receptors A1, A2A, A2B and A3 are important and ubiquitous
mediators of cellular signaling that play vital roles in protecting tissues and organs from …

Recent studies indicate a widening role for adenosine receptors in many therapeutic areas.
Adenosine receptors are involved in immunological and inflammatory responses, respiratory …