Direct Evidence for Catalase as the Predominant H2O2 -Removing Enzyme in Human Erythrocytes
S Mueller, HD Riedel… - Blood, The Journal of the …, 1997 - ashpublications.org
Decomposition of hydrogen peroxide (H2O2) at physiological levels was studied in human
erythrocytes by means of a recently developed sensitive H2O2 assay. The exponential …
erythrocytes by means of a recently developed sensitive H2O2 assay. The exponential …
Catalase and glutathione peroxidase are equally active in detoxification of hydrogen peroxide in human erythrocytes
GF Gaetani, S Galiano, L Canepa, AM Ferraris… - 1989 - ashpublications.org
Genetic deficiencies of glucose-6-phosphate dehydrogenase (G6PD) and NADPH
predispose affected erythrocytes to destruction from peroxides. Conversely, genetic …
predispose affected erythrocytes to destruction from peroxides. Conversely, genetic …
Importance of catalase in the disposal of hydrogen peroxide within human erythrocytes
GF Gaetani, HN Kirkman, R Mangerini, AM Ferraris - 1994 - ashpublications.org
The catalase within normal, intact human erythrocytes was completely inactivated with
amino triazole. The rate of 14CO2 evolution, when the cells were subsequently incubated …
amino triazole. The rate of 14CO2 evolution, when the cells were subsequently incubated …
Predominant role of catalase in the disposal of hydrogen peroxide within human erythrocytes
GF Gaetani, AM Ferraris, M Rolfo, R Mangerini… - 1996 - ashpublications.org
Purified enzymes were mixed to form a cell-free system that simulated the conditions for
removal of hydrogen peroxide within human erythrocytes. Human glutathione peroxidase …
removal of hydrogen peroxide within human erythrocytes. Human glutathione peroxidase …
Glutathione Peroxidase: The Primary Agent for the Elimination of Hydrogen Peroxide in Erythrocytes*
G Cohen, P Hochstein - Biochemistry, 1963 - ACS Publications
Experiments were designed to evaluate the competition between erythrocyte catalase and
glutathione peroxidase for their common substrate, H202. When extracellular H2O2 …
glutathione peroxidase for their common substrate, H202. When extracellular H2O2 …
Erythrocyte defense against hydrogen peroxide: preeminent importance of catalase
MD Scott, BH Lubin, L Zuo… - The Journal of laboratory …, 1991 - translationalres.com
To investigate the relative importance of catalase and glutathione in erythrocyte oxidant
defense, human and mouse (normal and acatalasemic) erythrocytes were reversibly lysed …
defense, human and mouse (normal and acatalasemic) erythrocytes were reversibly lysed …
Contributions of catalase and glutathione peroxidase to red cell peroxide removal
P Nicholls - Biochimica et Biophysica Acta (BBA)-General Subjects, 1972 - Elsevier
The contributions of catalase (H 2 O 2: H 2 O 2 oxidoreductase EC 1.11. 1.6) and glutathione
peroxidase (H 2 O 2: GSH oxidoreductase EC 1.11. 1.19) to the removal of H 2 O 2 from red …
peroxidase (H 2 O 2: GSH oxidoreductase EC 1.11. 1.19) to the removal of H 2 O 2 from red …
Erythrocyte catalase. A somatic oxidant defense?
NS Agar, SM Sadrzadeh, PE Hallaway… - The Journal of …, 1986 - Am Soc Clin Investig
Mammalian erythrocytes have large amounts of catalase, an enzyme which catabolizes
hydrogen peroxide (H2O2). Because catalase has a low affinity for H2O2, others have …
hydrogen peroxide (H2O2). Because catalase has a low affinity for H2O2, others have …
Hydrogen peroxide production by red blood cells
C Giulivi, P Hochstein, KJA Davies - Free Radical Biology and Medicine, 1994 - Elsevier
Red blood cells are frequently employed in studies of oxidative stress. Technical difficulties
have previously prevented the measurement of H 2 O 2 production by red blood cells …
have previously prevented the measurement of H 2 O 2 production by red blood cells …
Hydrogen-peroxide-induced heme degradation in red blood cells: the protective roles of catalase and glutathione peroxidase
E Nagababu, FJ Chrest, JM Rifkind - Biochimica et Biophysica Acta (BBA) …, 2003 - Elsevier
Catalase and glutathione peroxidase (GSHPX) react with red cell hydrogen peroxide. A
number of recent studies indicate that catalase is the primary enzyme responsible for …
number of recent studies indicate that catalase is the primary enzyme responsible for …