Recent advances in glomerular biology have expanded our understanding of glomerular
diseases, leading to more precise therapeutic options. Since the discovery of the …

Publisher Summary In its simplest definition, a biomarker is anything that can be measured
to extract information about a biological state or process. The NIH Biomarkers Definitions …

In the past decade there has been a sea change in the way disease is diagnosed and
investigated due to the advent of high throughput technologies, such as microarrays, lab on …

The use of reliable biomarkers is becoming increasingly important for the improved
management of patients with acute and chronic kidney diseases. Recent developments …

Effective management of glomerular kidney disease, one of the main categories of chronic
kidney disease (CKD), requires accurate diagnosis, prognosis of progression, assessment …

Glomerular diseases are major contributors to the global burden of end-stage kidney
disease. The clinical course and outcome of these disorders are extremely variable and …

The diagnosis and treatment decisions in glomerular disease are principally based on renal
pathology and nonspecific clinical laboratory measurements such as serum creatinine and …

One of the major challenges modern nephrology should face is the identification of
biomarkers that are associated with histopathological patterns or defined pathogenic …

Proteomic biomarkers offer the hope of improving the management of patients with kidney
diseases by enabling more accurate and earlier detection of renal pathology than is …

Data continue to emerge on applicable biomarkers for prognostic clinical risk stratification,
prediction of therapeutic response and assessment of early efficacy of interventions …