The aim of the present study was to investigate whether an increase in cyclin‑dependent
kinase 2 (CDK2) activity is involved in apoptosis of human bladder cancer T24 cells induced …

Sinularin is an active compound isolated from the cultured soft coral Sinularia flexibilis. In
this study, we investigated the effects of sinularin on two human gastric cancer cell lines …

Objective Herein, inhibition of hepatocyte growth factor receptor, c-Met, significantly
increased cytochrome c release and Bax/Bcl-2 ratio, indicating that c-Met played an anti …

Background Emodin is a natural anthraquinone derivative isolated from the Rheum
palmatum L. Aim: The aim of the present study was to investigate the effect of emodin on the …

This study is the first to investigate the anticancer effect of isoliquiritigenin (ISL) in human
cervical carcinoma HeLa cells. The results reveal that ISL inhibits HeLa cells by blocking cell …

Chemoprevention by the use of naturally occurring substances is becoming a promising
strategy to prevent cancer. In this study, the effects of isoobtusilactone A, a novel constituent …

Abstract Cirsilineol (4′, 5-dihydroxy-3′, 6, 7-trimethoxyflavone) is a compound isolated
from the herb of Artemisia vestita Wall (Compositae). In this study, we aimed at examining …

Isoliquiritigenin (ISL), a simple chalcone derivative, 4, 2′, 4′-trihydroxychalcone, found in
licorice, shallot and bean sprouts, has been reported to have chemoprotective effects. To …

Colorectal cancer (CRC) is one of the most common human malignant tumors worldwide.
Arising from the transformation of epithelial cells in the colon and/or rectum into malignant …

Background. Allicin, the major component of freshly crushed garlic, is one of the most
biologically active compounds of garlic; it has been reported to induce apoptosis in cancer …