Betulinic acid accelerates diabetic wound healing by modulating hyperglycemia-induced oxidative stress, inflammation and glucose intolerance

W Xie, W Hu, Z Huang, M Li, H Zhang, X Huang… - Burns & …, 2022 - academic.oup.com
Background Diabetes significantly delays wound healing through oxidative stress,
inflammation and impaired re-epithelialization that lead to defective regulation of the healing …

[HTML][HTML] Topical administration of pterostilbene accelerates burn wound healing in diabetes through activation of the HIF1α signaling pathway

W Hu, H Yu, X Zhou, M Li, L Xiao, Q Ruan, X Huang… - Burns, 2022 - Elsevier
Impaired wound healing is one of a variety of severe diabetic complications and involves
many factors, including consistent oxidative stress, prolonged inflammation, impaired …

Influence of birch bark triterpenes on keratinocytes and fibroblasts from diabetic and nondiabetic donors

T Wardecki, P Werner, M Thomas… - Journal of natural …, 2016 - ACS Publications
Impaired wound healing is one of the main risk factors associated with diabetes mellitus.
Few options are available to treat diabetic wounds, and therefore efficient remedies are …

Baicalin regulates mRNA expression of VEGF‐c, Ang‐1/Tie2, TGF‐β and Smad2/3 to inhibit wound healing in streptozotocin‐induced diabetic foot ulcer rats

X Mao, Z Li, B Li, H Wang - Journal of Biochemical and …, 2021 - Wiley Online Library
Diabetic foot ulcer (DFU) is biggest life threats globally and increases their severity
increases health complications for health of patients. The present study was investigated to …

Extract of Berula angustifolia (L.) Mertens Enhances Wound Healing in Streptozotocin-induced Diabetic Rats.

N Sanaei, R Mohammadi, A Raisi… - Wounds: A Compendium …, 2018 - europepmc.org
Objective The aim of this study is to assess the wound healing activity of the methanolic
extracts of Berula angustifolia leaves. Materials and methods Seven-week-old male Wistar …

[HTML][HTML] Huangbai liniment and berberine promoted wound healing in high-fat diet/Streptozotocin-induced diabetic rats

J Zhang, R Zhou, L Deng, G Cao, Y Zhang, H Xu… - Biomedicine & …, 2022 - Elsevier
Diabetic ulcer is a challenging complication of diabetes mellitus but current treatments
cannot achieve satisfactory results. In this study, the effect of Huangbai liniment (HB) and …

Boron promotes streptozotocin-induced diabetic wound healing: roles in cell proliferation and migration, growth factor expression, and inflammation

S Demirci, A Doğan, S Aydın, EÇ Dülger… - Molecular and cellular …, 2016 - Springer
Acute wounds do not generally require professional treatment modalities and heal in a
predictable fashion, but chronic wounds are mainly accompanied with infection and …

[HTML][HTML] Sinapic acid-loaded gel accelerates diabetic wound healing process by promoting re-epithelialization and attenuating oxidative stress in rats

K Kaltalioglu - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Impaired wound healing is a critical health concern for individuals with diabetes. Sinapic
acid, a phyto-compound, has wound-healing potential owing to its various bioactivities. In …

[HTML][HTML] Pien-tze-huang promotes wound healing in streptozotocin-induced diabetes models associated with improving oxidative stress via the Nrf2/ARE pathway

Y Liu, J Mo, F Liang, S Jiang, J Xiong… - Frontiers in …, 2023 - frontiersin.org
Diabetic foot ulcers are a serious complication of diabetes, with high mortality and a lack of
effective clinical treatment, which leads to a considerable financial burden. Pien-Tze-Huang …

Betulinic acid inhibits high glucose‐induced vascular smooth muscle cells proliferation and migration

JJ Yoon, YJ Lee, JS Kim, DG Kang… - Journal of cellular …, 2010 - Wiley Online Library
The proliferation of vascular smooth muscle cells may perform a crucial role in the
pathogenesis of diabetic vascular disease. The principal objective of this study was to …