Antiangiogenic mechanisms of diet-derived polyphenols

Y Cao, R Cao, E Bråkenhielm - The Journal of Nutritional Biochemistry, 2002 - Elsevier
Accumulating evidence demonstrates that polyphenols in natural products are beneficial
against human lethal diseases such as cancer and metastasis. The underlying mechanisms …

Polyphenol-based nutraceuticals for the control of angiogenesis: Analysis of the critical issues for human use

L Morbidelli - Pharmacological Research, 2016 - Elsevier
Angiogenesis, the formation of new blood-vessel, is crucial in the pathogenesis of several
diseases, and thus represents a druggable target for the prevention and treatment of …

Antiangiogenic properties of natural polyphenols from red wine and green tea

MH Oak, J El Bedoui, VB Schini-Kerth - The Journal of nutritional …, 2005 - Elsevier
Epidemiological studies have indicated that regular consumption of red wine and green tea
is associated with a reduced risk of coronary heart disease and tumor progression. The …

Nutraceuticals as anti-angiogenic agents: hopes and reality

J Dulak - Journal of Physiology and Pharmacology. Supplement, 2005 - agro.icm.edu.pl
Angiogenesis, the formation of new blood vessels from preexisting vascular network is a
driving force of organ development in ontogeny, is necessary for ovulation and hair growth …

'Angioprevention': angiogenesis is a common and key target for cancer chemopreventive agents

F Tosetti, N Ferrari, S De Flora, A Albini - The FASEB Journal, 2002 - Wiley Online Library
The potential to block tumor growth by inhibition of the neoangiogenic process represents
an intriguing approach to the treatment of solid tumors. The high proliferation rate in the …

Genistein, a dietary-derived inhibitor of in vitro angiogenesis.

T Fotsis, M Pepper, H Adlercreutz… - Proceedings of the …, 1993 - National Acad Sciences
Consumption of a plant-based diet can prevent the development and progression of chronic
diseases that are associated with extensive neovascularization; however, little is known …

Dietary polyphenols regulate endothelial function and prevent cardiovascular disease

K Yamagata, M Tagami, Y Yamori - Nutrition, 2015 - Elsevier
Vascular endothelial cell (EC) dysfunction strongly induces development of cardiovascular
and cerebrovascular diseases. Epidemiologic studies demonstrated a preventative effect of …

Natural health products that inhibit angiogenesis: a potential source for investigational new agents to treat cancer—Part 1

SM Sagar, D Yance, RK Wong - Current Oncology, 2006 - mdpi.com
An integrative approach for managing a patient with cancer should target the multiple
biochemical and physiologic pathways that support tumour development and minimize …

Vascular protection by dietary polyphenols

JC Stoclet, T Chataigneau, M Ndiaye, MH Oak… - European journal of …, 2004 - Elsevier
Consumption of polyphenol-rich foods, such as fruits and vegetables, and beverages
derived from plants, such as cocoa, red wine and tea, may represent a beneficial diet in …

Different effects of catechin on angiogenesis and inflammation depending on VEGF levels

R Negrão, R Costa, D Duarte, TT Gomes… - The Journal of …, 2013 - Elsevier
Although physiological and pathological angiogenesis develop through similar processes,
during pathological angiogenesis, proangiogenic factors are exacerbated. Polyphenols …