Can we reduce the incidence of second primary malignancies occurring after radiotherapy? A critical review

M Tubiana - Radiotherapy and Oncology, 2009 - Elsevier
Second primary malignancies (SPMs) occurring after oncological treatment have become a
major concern during the past decade. Their incidence has long been underestimated …

Risk of a second malignant neoplasm after cancer in childhood treated with radiotherapy: correlation with the integral dose restricted to the irradiated fields

F Nguyen, C Rubino, S Guerin, I Diallo… - International Journal of …, 2008 - Elsevier
PURPOSE: After successful treatment of cancers in childhood, the occurrence of second
malignant neoplasm (SMN) came to the fore. Few studies have considered the relationship …

[HTML][HTML] Current knowledge and future research directions in treatment-related second primary malignancies

LM Morton, AJ Swerdlow, M Schaapveld… - European Journal of …, 2014 - Elsevier
Abstract Currently, 17–19% of all new primary malignancies occur in survivors of cancer,
causing substantial morbidity and mortality. Research has shown that cancer treatments are …

Second malignant neoplasms following radiotherapy

S Kumar - International journal of environmental research and …, 2012 - mdpi.com
More than half of all cancer patients receive radiotherapy as a part of their treatment. With
the increasing number of long-term cancer survivors, there is a growing concern about the …

Secondary carcinogenesis in patients treated with radiation: a review of data on radiation-induced cancers in human, non-human primate, canine and rodent subjects

H Suit, S Goldberg, A Niemierko… - Radiation …, 2007 - meridian.allenpress.com
Abstract Suit, H., Goldberg, S., Niemierko, A., Ancukiewicz, M., Hall, E., Goitein, M., Wong, W.
and Paganetti, H. Secondary Carcinogenesis in Patients Treated with Radiation: A Review …

Proportion of second cancers attributable to radiotherapy treatment in adults: a cohort study in the US SEER cancer registries

AB De Gonzalez, RE Curtis, SF Kry, E Gilbert… - The lancet …, 2011 - thelancet.com
Background Improvements in cancer survival have made the long-term risks from treatments
more important, including the risk of developing a second cancer after radiotherapy. We …

Intensity-modulated radiation therapy, protons, and the risk of second cancers

EJ Hall - International Journal of Radiation Oncology* Biology …, 2006 - Elsevier
Intensity-modulated radiation therapy (IMRT) allows dose to be concentrated in the tumor
volume while sparing normal tissues. However, the downside to IMRT is the potential to …

Radiation-induced second cancers: the impact of 3D-CRT and IMRT

EJ Hall, CS Wuu - International Journal of Radiation Oncology* Biology …, 2003 - Elsevier
Information concerning radiation-induced malignancies comes from the A-bomb survivors
and from medically exposed individuals, including second cancers in radiation therapy …

Assessing the risk of second malignancies after modern radiotherapy

WD Newhauser, M Durante - Nature Reviews Cancer, 2011 - nature.com
Recent advances in radiotherapy have enabled the use of different types of particles, such
as protons and heavy ions, as well as refinements to the treatment of tumours with standard …

The effect of intensity-modulated radiotherapy on radiation-induced second malignancies

JD Ruben, S Davis, C Evans, P Jones… - International Journal of …, 2008 - Elsevier
PURPOSE: To compare intensity-modulated radiotherapy (IMRT) with three-dimensional
conformal radiotherapy (3D-CRT) in terms of carcinogenic risk for actual clinical scenarios …