[HTML][HTML] Parabacteroides distasonis uses dietary inulin to suppress NASH via its metabolite pentadecanoic acid
Non-alcoholic steatohepatitis (NASH) is the severe form of non-alcoholic fatty liver disease,
and is characterized by liver inflammation and fat accumulation. Dietary interventions, such …
and is characterized by liver inflammation and fat accumulation. Dietary interventions, such …
[HTML][HTML] Commensal microbe-derived acetate suppresses NAFLD/NASH development via hepatic FFAR2 signalling in mice
R Aoki, M Onuki, K Hattori, M Ito, T Yamada… - Microbiome, 2021 - Springer
Background Non-alcoholic liver disease (NAFLD) is the hepatic manifestation of metabolic
syndrome, and it can progress to non-alcoholic steatohepatitis (NASH). Alterations in the gut …
syndrome, and it can progress to non-alcoholic steatohepatitis (NASH). Alterations in the gut …
The role of the microbiome in NAFLD and NASH
AA Kolodziejczyk, D Zheng, O Shibolet… - EMBO molecular …, 2019 - embopress.org
Nonalcoholic fatty liver disease (NAFLD) is the hepatic manifestation of cardiometabolic
syndrome, which often also includes obesity, diabetes, and dyslipidemia. It is rapidly …
syndrome, which often also includes obesity, diabetes, and dyslipidemia. It is rapidly …
[HTML][HTML] Non-alcoholic fatty liver and the gut microbiota
S Bashiardes, H Shapiro, S Rozin, O Shibolet… - Molecular …, 2016 - Elsevier
Background Non-alcoholic fatty liver (NAFLD) is a common, multi-factorial, and poorly
understood liver disease whose incidence is globally rising. NAFLD is generally …
understood liver disease whose incidence is globally rising. NAFLD is generally …
[HTML][HTML] Trimethylamine-N-oxide (TMAO) mediates the crosstalk between the gut microbiota and hepatic vascular niche to alleviate liver fibrosis in nonalcoholic …
Liver fibrosis is one main histological characteristic of nonalcoholic steatohepatitis (NASH),
a disease paralleling a worldwide surge in metabolic syndromes with no approved …
a disease paralleling a worldwide surge in metabolic syndromes with no approved …
Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women
Hepatic steatosis is a multifactorial condition that is often observed in obese patients and is
a prelude to non-alcoholic fatty liver disease. Here, we combine shotgun sequencing of fecal …
a prelude to non-alcoholic fatty liver disease. Here, we combine shotgun sequencing of fecal …
[HTML][HTML] Distinct signatures of gut microbiome and metabolites associated with significant fibrosis in non-obese NAFLD
G Lee, HJ You, JS Bajaj, SK Joo, J Yu, S Park… - Nature …, 2020 - nature.com
Nonalcoholic fatty liver disease (NAFLD) is associated with obesity but also found in non-
obese individuals. Gut microbiome profiles of 171 Asians with biopsy-proven NAFLD and 31 …
obese individuals. Gut microbiome profiles of 171 Asians with biopsy-proven NAFLD and 31 …
Longitudinal 16S rRNA sequencing reveals relationships among alterations of gut microbiota and nonalcoholic fatty liver disease progression in mice
A Zhuge, S Li, P Lou, W Wu, K Wang, Y Yuan… - Microbiology …, 2022 - Am Soc Microbiol
Nonalcoholic fatty liver disease (NAFLD) is a prevalent and progressive disease spectrum
ranging from nonalcoholic fatty liver (NAFL) to nonalcoholic steatohepatitis (NASH), yet …
ranging from nonalcoholic fatty liver (NAFL) to nonalcoholic steatohepatitis (NASH), yet …
[HTML][HTML] Disulfiram ameliorates nonalcoholic steatohepatitis by modulating the gut microbiota and bile acid metabolism
Y Lei, L Tang, Q Chen, L Wu, W He, D Tu… - Nature …, 2022 - nature.com
Nonalcoholic steatohepatitis (NASH) has been linked with the gut-liver axis. Here, we
investigate the potential for repurposing disulfiram (DSF), a drug commonly used to treat …
investigate the potential for repurposing disulfiram (DSF), a drug commonly used to treat …
[HTML][HTML] Lentinan supplementation protects the gut–liver axis and prevents steatohepatitis: The role of gut microbiota involved
X Yang, M Zheng, M Zhou, L Zhou, X Ge, N Pang… - Frontiers in …, 2022 - frontiersin.org
The microbiota–gut–liver axis has emerged as an important player in developing
nonalcoholic steatohepatitis (NASH), a type of nonalcoholic fatty liver disease (NAFLD) …
nonalcoholic steatohepatitis (NASH), a type of nonalcoholic fatty liver disease (NAFLD) …