The Corynebacterium glutamicum genome: features and impacts on biotechnological processes

M Ikeda, S Nakagawa - Applied microbiology and biotechnology, 2003 - Springer
Corynebacterium glutamicum has played a principal role in the progress of the amino acid
fermentation industry. The complete genome sequence of the representative wild-type strain …

Tools for genetic manipulations in Corynebacterium glutamicum and their applications

J Nešvera, M Pátek - Applied microbiology and biotechnology, 2011 - Springer
Corynebacterium glutamicum is an important industrial producer of various amino acids with
great potential for the production of other metabolites. The complete genome sequences of …

Emerging Corynebacterium glutamicum systems biology

VF Wendisch, M Bott, J Kalinowski, M Oldiges… - Journal of …, 2006 - Elsevier
Corynebacterium glutamicum is widely used for the biotechnological production of amino
acids. Amino acid producing strains have been improved classically by mutagenesis and …

Comparative analysis of the Corynebacterium glutamicum group and complete genome sequence of strain R

H Yukawa, CA Omumasaba, H Nonaka… - …, 2007 - microbiologyresearch.org
The complete genome sequence of Corynebacterium glutamicum strain R was determined
to allow its comparative analysis with other corynebacteria. The biology of corynebacteria …

Biosystem design of Corynebacterium glutamicum for bioproduction

J Zha, Z Zhao, Z Xiao, T Eng, A Mukhopadhyay… - Current Opinion in …, 2023 - Elsevier
Highlights•Corynebacterium glutamicum has been used for many applications beyond
amino acids.•Economical, high-quality genome assemblies foster development of non-type …

The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins

J Kalinowski, B Bathe, D Bartels, N Bischoff, M Bott… - Journal of …, 2003 - Elsevier
The complete genomic sequence of Corynebacterium glutamicum ATCC 13032, well-known
in industry for the production of amino acids, eg of l-glutamate and l-lysine was determined …

New Multiple-Deletion Method for the Corynebacterium glutamicum Genome, Using a Mutant lox Sequence

N Suzuki, H Nonaka, Y Tsuge, M Inui… - Applied and …, 2005 - Am Soc Microbiol
Due to the difficulty of multiple deletions using the Cre/loxP system, a simple, markerless
multiple-deletion method based on a Cre/mutant lox system combining a right-element (RE) …

Transcriptome Analysis of Acetate Metabolism in Corynebacterium glutamicum Using a Newly Developed Metabolic Array

M Hayashi, H Mizoguchi, N Shiraishi… - Bioscience …, 2002 - academic.oup.com
Following the determination of the whole-genome sequence of Corynebacterium
glutamicum, we have developed a DNA array to extensively investigate gene expression …

Development and experimental verification of a genome-scale metabolic model for Corynebacterium glutamicum

Y Shinfuku, N Sorpitiporn, M Sono, C Furusawa… - Microbial cell …, 2009 - Springer
Background In silico genome-scale metabolic models enable the analysis of the
characteristics of metabolic systems of organisms. In this study, we reconstructed a genome …

Corynebacterium glutamicum for Sustainable Bioproduction: From Metabolic Physiology to Systems Metabolic Engineering

J Becker, G Gießelmann, SL Hoffmann… - Synthetic biology …, 2018 - Springer
Since its discovery 60 years ago, Corynebacterium glutamicum has evolved into a
workhorse for industrial biotechnology. Traditionally well known for its remarkable capacity …