One‐year safety and efficacy of ustekinumab and results of dose adjustment after switching from inadequate methotrexate treatment: the TRANSIT randomized trial in …
Background There are limited long‐term,'real‐world'data on ustekinumab, or the effect of
dose adjustment in suboptimal responders. Objectives We describe 52‐week data from …
dose adjustment in suboptimal responders. Objectives We describe 52‐week data from …
Transition to ustekinumab in patients with moderate‐to‐severe psoriasis and inadequate response to methotrexate: a randomized clinical trial (TRANSIT)
Background Limited data exist on transitioning patients with psoriasis from conventional
systemic agents to biologics. Objectives The TRANSIT study aimed to assess the efficacy …
systemic agents to biologics. Objectives The TRANSIT study aimed to assess the efficacy …
Long‐term efficacy and safety of ustekinumab, with and without dosing adjustment, in patients with moderate‐to‐severe psoriasis: results from the PHOENIX 2 study …
RG Langley, M Lebwohl, GG Krueger… - British Journal of …, 2015 - academic.oup.com
Background Evaluation of the dosing flexibility and long‐term efficacy of biological agents is
limited. Objectives To evaluate the long‐term efficacy and safety of ustekinumab with and …
limited. Objectives To evaluate the long‐term efficacy and safety of ustekinumab with and …
Ustekinumab treatment for moderate to severe psoriasis. Eight-year real-world follow-up of 61 cases in a tertiary level hospital
L Elberdín, R Fernández-Torres… - Journal of …, 2019 - Taylor & Francis
Background: Efficacy and safety profiles of ustekinumab have been proved in numerous
clinical trials. However, relevant variations with daily practice have been shown and few …
clinical trials. However, relevant variations with daily practice have been shown and few …
Extension of ustekinumab maintenance dosing interval in moderate‐to‐severe psoriasis: results of a phase IIIb, randomized, double‐blinded, active‐controlled …
A Blauvelt, LK Ferris, PS Yamauchi… - British Journal of …, 2017 - academic.oup.com
Background Phase III studies showed that some patients maintained response for≥ 6
months following ustekinumab discontinuation. Objectives To assess clinical responses with …
months following ustekinumab discontinuation. Objectives To assess clinical responses with …
Long‐term efficacy of ustekinumab in patients with moderate‐to‐severe psoriasis: results from the PHOENIX 1 trial through up to 3 years
AB Kimball, KB Gordon, S Fakharzadeh… - British Journal of …, 2012 - academic.oup.com
Background An unmet need remains for safe and effective long‐term treatments of psoriasis.
Objectives To evaluate ustekinumab efficacy and safety for up to 3 years in the PHOENIX 1 …
Objectives To evaluate ustekinumab efficacy and safety for up to 3 years in the PHOENIX 1 …
Ustekinumab dosing, persistence, and discontinuation patterns in patients with moderate-to-severe psoriasis
Z Cao, C Carter, KL Wilson… - Journal of Dermatological …, 2015 - Taylor & Francis
Objectives: Ustekinumab is the most recently approved biologic for the treatment of
moderate-to-severe psoriasis. Real-world dosing patterns of ustekinumab are yet to be fully …
moderate-to-severe psoriasis. Real-world dosing patterns of ustekinumab are yet to be fully …
Systematic review and meta‐analysis of ustekinumab for moderate to severe psoriasis
Y Meng, L Dongmei, P Yanbin, F Jinju… - Clinical and …, 2014 - academic.oup.com
Background Psoriasis is a chronic, recurrent skin disease that affects approximately 2–3% of
the world's population, and can significantly impair patients' wellbeing and their physical and …
the world's population, and can significantly impair patients' wellbeing and their physical and …
Long-term safety experience of ustekinumab in patients with moderate-to-severe psoriasis (Part I of II): results from analyses of general safety parameters from pooled …
M Lebwohl, C Leonardi, CEM Griffiths, JC Prinz… - Journal of the American …, 2012 - Elsevier
BACKGROUND: Ustekinumab targets interleukin (IL)-12 and IL-23 in the treatment of
moderate-to-severe psoriasis. OBJECTIVE: To evaluate overall pooled study data to assess …
moderate-to-severe psoriasis. OBJECTIVE: To evaluate overall pooled study data to assess …
Ustekinumab treatment for moderate-to-severe plaque psoriasis: eight-year real-life experience
M Galluzzo, S D'Adamio, D Silvaggio… - Expert Opinion on …, 2020 - Taylor & Francis
Background: Limited information is available from real-life studies evaluating the long-term
efficacy and drug retention of ustekinumab. Research design and methods: Data from 378 …
efficacy and drug retention of ustekinumab. Research design and methods: Data from 378 …