Flavonoids: classification, function, and molecular mechanisms involved in bone remodelling

P Ramesh, R Jagadeesan, S Sekaran… - Frontiers in …, 2021 - frontiersin.org
Flavonoids are polyphenolic compounds spotted in various fruits, vegetables, barks, tea
plants, and stems and many more natural commodities. They have a multitude of …

Functions and action mechanisms of flavonoids genistein and icariin in regulating bone remodeling

LG Ming, KM Chen, CJ Xian - Journal of cellular physiology, 2013 - Wiley Online Library
Increasingly natural products particularly flavonoids are being explored for their therapeutic
potentials in reducing bone loss and maintaining bone health. This study has reviewed …

Modulatory effects of plant polyphenols on bone remodeling: a prospective view from the bench to bedside

V Nicolin, N De Tommasi, SL Nori… - Frontiers in …, 2019 - frontiersin.org
During the past, a more comprehensive knowledge of mechanisms implicated in bone
resorption processes has driven researchers to develop a compound library of many small …

Molecular signaling mechanisms behind polyphenol-induced bone anabolism

E Torre - Phytochemistry Reviews, 2017 - Springer
For millennia, in the different cultures all over the world, plants have been extensively used
as a source of therapeutic agents with wide-ranging medicinal applications, thus becoming …

Flavonoids in bone erosive diseases: perspectives in osteoporosis treatment

D Bellavia, E Dimarco, V Costa, V Carina… - Trends in Endocrinology …, 2021 - cell.com
Imbalance of bone homeostasis, with excessive bone resorption compared with bone
formation, leads to the development of progressive osteopenia leading to lower bone …

Polyphenols as potential preventers of osteoporosis: A comprehensive review on antioxidant and anti-inflammatory effects, molecular mechanisms, and signal …

Z Su, B Yao, G Liu, J Fang - The Journal of Nutritional Biochemistry, 2023 - Elsevier
Osteoporosis (OP) is a skeletal disorder characterized by decreased bone density,
alterations in bone microstructure, and increased damage to the bones. As the population …

The effects of flavonoids on bone

AA Welch, AC Hardcastle - Current osteoporosis reports, 2014 - Springer
Osteoporosis and fragility fractures are a growing problem for our aging population with
around 1 in 2 women and 1 in 5 men suffering from an osteoporotic fracture during their …

Flavonoid intake and bone health

CM Weaver, DL Alekel, WE Ward… - Journal of nutrition in …, 2012 - Taylor & Francis
Flavonoids, found in a wide diversity of plant foods from fruits and vegetables, herbs and
spices, essential oils, and beverages, have the most potential of dietary components for …

Quercetin as an agent for protecting the bone: a review of the current evidence

SK Wong, KY Chin, S Ima-Nirwana - International journal of molecular …, 2020 - mdpi.com
Quercetin is a flavonoid abundantly found in fruits and vegetables. It possesses a wide
spectrum of biological activities, thus suggesting a role in disease prevention and health …

Dietary nutraceuticals as backbone for bone health

MK Pandey, SC Gupta, D Karelia, PJ Gilhooley… - Biotechnology …, 2018 - Elsevier
Bone loss or osteoporosis, is a slow-progressing disease that results from dysregulation of
pro-inflammatory cytokines. The FDA has approved number of drugs for bone loss …