Idiopathic Pulmonary Fibrosis (IPF) is a chronic interstitial lung disease which results in end-
stage fibrosis. The pathogenesis is believed to be related to a dysregulation in cross-talk …

Organ fibrosis, the result of exaggerated, persistent, and often irreversible accumulation of
extracellular matrix, complicates numerous diseases in all organs and tissues and has …

Pulmonary fibrosis is characterized by lung inflammation and abnormal tissue repair,
resulting in the replacement of normal functional tissue with an abnormal accumulation of …

Idiopathic pulmonary fibrosis (IPF) exhibits a complex and poorly understood pathogenesis.
Overt inflammation in the lungs of patients with established IPF is absent, and classic anti …

Idiopathic pulmonary fibrosis (IPF) is a progressive and irreversible fibrosing lung disease of
unknown etiology and with an unfavorable outcome, leading ultimately to death due to …

The mechanisms of pulmonary fibrosis are complex, and several hypotheses have been put
forward to explain how fibrosis develops. It was long thought that inflammation was a key …

Fibrosis is a disorder characterized by a qualitative and quantitative alteration of the
deposition of extracellular matrix with accumulation of mesenchymal cells in replacement of …

A recent review article suggested that idiopathic pulmonary fibrosis (IPF) is a disease that is
associated more with abnormal wound healing than with inflammation. Data derived from …

Fibrotic process affecting the lung and other tissues is characterized by stimulation of
fibroblast proliferation and connective tissue deposition. Conventional therapy consisting of …

The pathogenesis of end-stage, chronic lung disease is thought to be characterized by an
initial inflammatory response followed by fibroproliferation and deposition of extracellular …