Differential histone modification status of spermatozoa in relation to fertility of buffalo bulls

A Verma, S Rajput, S Kumar, S De… - Journal of cellular …, 2015 - Wiley Online Library
In this study genome‐wide di‐methylated H3K4 (H3K4me2) and tri‐methylated H3K27
(H3K27me3) modification profiles were analyzed in spermatozoa of buffalo bulls having …

Acetylation and methylation of sperm histone 3 lysine 27 (H3K27ac and H3K27me3) are associated with bull fertility

NA Kutchy, ESB Menezes, A Chiappetta, W Tan… - Andrologia, 2018 - Wiley Online Library
Epigenetic modifications in histones are crucial for proper sperm physiology, egg activation
and reproductive development of males. The objectives of this study were to determine the …

[HTML][HTML] Retained acetylated histone four in bull sperm associated with fertility

MR Ugur, NA Kutchy, EB Menezes… - Frontiers in Veterinary …, 2019 - frontiersin.org
Bull fertility, ability of the sperm to fertilize and activate the egg and support embryo
development, is vital for cattle reproduction and production. Even though majority of histones …

[HTML][HTML] Testis specific histone 2B is associated with sperm chromatin dynamics and bull fertility-a pilot study

NA Kutchy, A Velho, ESB Menezes, M Jacobsen… - Reproductive Biology …, 2017 - Springer
Background Bull fertility is the degree of sperm's ability to fertilize and activate the egg and
support embryo development, and this is critical for herd reproductive performance. We used …

Genome-wide profiling of sperm DNA methylation in relation to buffalo (Bubalus bubalis) bull fertility

A Verma, S Rajput, S De, R Kumar, AK Chakravarty… - Theriogenology, 2014 - Elsevier
The DNA methylation pattern in spermatozoa of buffalo bulls of different fertility status was
investigated. Spermatozoa isolated DNA from two groups of buffalo bulls (n= 5), selected …

[HTML][HTML] Altered histone retention and epigenetic modifications in the sperm of infertile men

R Oliva, JL Ballescà - Asian journal of andrology, 2012 - ncbi.nlm.nih.gov
It is well know that the nuclei of spermato-genic cells experience one of the most extremely
marked chromatin changes known in cells. At the end of spermatogenesis, the histones are …

Sperm chromatin integrity and DNA methylation in Norwegian Red bulls of contrasting fertility

B Narud, A Khezri, TT Zeremichael… - Molecular …, 2021 - Wiley Online Library
In this study, the complexity of chromatin integrity was investigated in frozen‐thawed semen
samples from 37 sires with contrasting fertility, expressed as 56‐day non‐return rates …

[PDF][PDF] Molecular morphology and function of bull spermatozoa linked to histones and associated with fertility

RV De Oliveira, S Dogan, LE Belser, A Kaya… - Reproduction, 2013 - academia.edu
Sub-par fertility in bulls is influenced by alterations in sperm chromatin, and it might not be
solved with increased sperm concentration in artificial insemination. Appropriate histone …

Histone methylation regulates gene expression in the round spermatids to set the RNA payloads of sperm

S Sarkar, S Yadav, P Mehta, G Gupta… - Reproductive Sciences, 2022 - Springer
Gene expression during spermatogenesis undergoes significant changes due to a
demanding sequence of mitosis, meiosis, and differentiation. We investigated the …

Histone lysine methylation exhibits a distinct distribution during spermatogenesis in pigs

J An, J Qin, Y Wan, Y Zhang, Y Hu, C Zhang, W Zeng - Theriogenology, 2015 - Elsevier
Spermatogenesis is a continual process throughout the adult life of a male, which is
governed by unique transcriptional regulation and massive alterations of chromatin. Histone …