The possible dual role of the ACE2 receptor in asthma and coronavirus (SARS-CoV2) infection

ACCC Branco, MN Sato, RW Alberca - Frontiers in Cellular and …, 2020 - frontiersin.org
A new virus belonging to the coronaviridae family has been identified and named severe
acute respiratory syndrome coronavirus-2 (SARS-CoV-2)(Zhu et al., 2020). This virus can …

Effects of cigarette smoking on SARS‐CoV‐2 receptor ACE2 expression in the respiratory epithelium

IH Heijink, TL Hackett, SD Pouwels - The Journal of pathology, 2021 - Wiley Online Library
Abstract Due to the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS‐CoV‐2)
pandemic, the world is currently facing high morbidity and mortality rates as well as severe …

Advances in research on ACE2 as a receptor for 2019-nCoV

J Wu, W Deng, S Li, X Yang - Cellular and Molecular Life Sciences, 2021 - Springer
Currently, a novel coronavirus (SARS-CoV-2, also called 2019-nCoV) has triggered
pandemic Coronavirus Disease 2019 (COVID-19), an acute infectious respiratory disease …

Expression of ACE2 in airways: Implication for COVID‐19 risk and disease management in patients with chronic inflammatory respiratory diseases

Y Yao, H Wang, Z Liu - Clinical & Experimental Allergy, 2020 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19), caused by the novel severe acute
respiratory syndrome coronavirus 2 (SARS‐CoV‐2), has been a rising international cause of …

Network-based analysis between SARS-CoV-2 receptor ACE2 and common host factors in COVID-19 and asthma: Potential mechanistic insights

Q Yan, XY Lin, CW Peng, WJ Zheng, XH Liu… - … Signal Processing and …, 2024 - Elsevier
ACE2 as a functional receptor for SARS coronavirus plays an important role in COVID-19
infection of the host. Thus, we aimed to explore interaction networks between ACE2 and …

AXL is a candidate receptor for SARS-CoV-2 that promotes infection of pulmonary and bronchial epithelial cells

S Wang, Z Qiu, Y Hou, X Deng, W Xu, T Zheng, P Wu… - Cell research, 2021 - nature.com
The current coronavirus disease 2019 (COVID-19) pandemic presents a global public health
challenge. The viral pathogen responsible, severe acute respiratory syndrome coronavirus 2 …

Assessing ACE2 expression patterns in lung tissues in the pathogenesis of COVID-19

G Li, X He, L Zhang, Q Ran, J Wang, A Xiong… - Journal of …, 2020 - Elsevier
It has been reported that SARS-CoV-2 may use ACE2 as a receptor to gain entry into human
cells, in a way similar to that of SARS-CoV. Analyzing the distribution and expression level of …

Expression of the SARS-CoV-2 ACE2 Receptor in the Human Airway Epithelium

H Zhang, MR Rostami, PL Leopold… - American journal of …, 2020 - atsjournals.org
Rationale: Infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) causes coronavirus disease (COVID-19), a predominantly respiratory illness. The first …

Overexpression of the SARS‐CoV‐2 receptor ACE2 is induced by cigarette smoke in bronchial and alveolar epithelia

A Liu, X Zhang, R Li, M Zheng, S Yang… - The Journal of …, 2021 - Wiley Online Library
Abstract Angiotensin‐converting enzyme 2 (ACE2) has been identified as the functional
receptor of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) and a target for …

Possible transmission flow of SARS-CoV-2 based on ACE2 features

SS Hassan, S Ghosh, D Attrish, PP Choudhury… - Molecules, 2020 - mdpi.com
Angiotensin-converting enzyme 2 (ACE2) is the cellular receptor for the Severe Acute
Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) that is engendering the severe …