967. Inhibition of host neuraminidase increases susceptibility to invasive pulmonary aspergillosis
F Van De Veerdonk Jr, I Dewi, C Cunha… - Open Forum …, 2018 - ncbi.nlm.nih.gov
Background Influenza-associated aspergillosis (IAA) is an emerging fungal infection with
high mortality and morbidity and the pathogenesis of this disease is not well understood …
high mortality and morbidity and the pathogenesis of this disease is not well understood …
[HTML][HTML] Neuraminidase and SIGLEC15 modulate the host defense against pulmonary aspergillosis
Influenza-associated pulmonary aspergillosis (IAPA) has been reported increasingly since
the advent of use of neuraminidase (NA) inhibitors following the 2009 influenza pandemic …
the advent of use of neuraminidase (NA) inhibitors following the 2009 influenza pandemic …
Early oseltamivir reduces risk for influenza-associated aspergillosis in a double-hit murine model
L Seldeslachts, L Vanderbeke, A Fremau… - Virulence, 2021 - Taylor & Francis
Invasive pulmonary aspergillosis (IPA) is a life-threatening fungal infection occurring mainly
in immunocompromised patients. We recently identified IPA as an emerging co-infection …
in immunocompromised patients. We recently identified IPA as an emerging co-infection …
Dysregulated pulmonary inflammatory responses exacerbate the outcome of secondary aspergillosis following influenza
CK Lee, LVN Oliveira, A Akalin, CA Specht… - Mbio, 2023 - Am Soc Microbiol
Inhalation of airborne conidia of the ubiquitous fungus Aspergillus fumigatus commonly
occurs but invasive aspergillosis is rare except in profoundly immunocompromised persons …
occurs but invasive aspergillosis is rare except in profoundly immunocompromised persons …
Invasive aspergillosis associated with severe influenza infection
N Crum-Cianflone - Open Forum Infectious Diseases, 2016 - academic.oup.com
Background. Bacterial superinfections are well-described complications of influenza
infection, however few data exist on invasive fungal infections in this setting. The …
infection, however few data exist on invasive fungal infections in this setting. The …
Development of a corticosteroid-immunosuppressed mouse model to study the pathogenesis and therapy of influenza-associated pulmonary aspergillosis
S Wurster, J Pantaleón García, ND Albert… - The Journal of …, 2023 - academic.oup.com
Influenza-associated pulmonary aspergillosis (IAPA) is a feared complication in patients with
influenza tracheobronchitis, especially those receiving corticosteroids. Herein, we …
influenza tracheobronchitis, especially those receiving corticosteroids. Herein, we …
Postinfluenza Environment Reduces Aspergillus fumigatus Conidium Clearance and Facilitates Invasive Aspergillosis In Vivo
KW Liu, MS Grau, JT Jones, X Wang, EM Vesely… - MBio, 2022 - Am Soc Microbiol
Aspergillus fumigatus is a human fungal pathogen that is most often avirulent in
immunecompetent individuals because the innate immune system is efficient at eliminating …
immunecompetent individuals because the innate immune system is efficient at eliminating …
Clinical and microbiological characteristics of culture-positive, influenza-associated pulmonary aspergillosis: a single-center study in southern Taiwan, 2016–2019
CJ Wu, CT Cia, HC Wang, CW Chen, WC Lin, JC Lee… - Journal of Fungi, 2022 - mdpi.com
This study delineated the characteristics of 24 (11.2%) culture-positive, influenza-associated
pulmonary aspergillosis (IAPA) patients out of 215 patients with severe influenza during …
pulmonary aspergillosis (IAPA) patients out of 215 patients with severe influenza during …
[HTML][HTML] The influenza A virus promotes fungal growth of Aspergillus fumigatus via direct interaction in vitro
S König, J Schroeder, S Nietzsche, T Heinekamp… - Microbes and …, 2024 - Elsevier
Seasonal influenza A virus (IAV) infections still pose a major burden for public health
worldwide. Severe disease progression or even death is often related to superinfections of …
worldwide. Severe disease progression or even death is often related to superinfections of …
Invasive aspergillosis associated with severe influenza infections
NF Crum-Cianflone - Open Forum Infectious Diseases, 2016 - academic.oup.com
Background. Invasive aspergillosis may occur in the setting of severe influenza infections
due to viral-induced respiratory epithelium disruption and impaired immune effects, but data …
due to viral-induced respiratory epithelium disruption and impaired immune effects, but data …