Prognostic value of serum Krebs von den Lungen-6 (KL-6) levels in COVID-19 pneumonia

A Letellier, C Rolland-Debord, D Luque-Paz… - … Medicine and Research, 2023 - Elsevier
Background and objectives Krebs von den Lungen-6 (KL-6), expressed by damaged type II
pneumocytes, is useful in the diagnosis and severity assessment of many diffuse interstitial …

Clinical relevance of serum Krebs von den Lungen-6 levels in patients with coronavirus disease 2019

H Chen, R Qin, Z Huang, W Luo, P Zheng, H Huang… - Cytokine, 2021 - Elsevier
The clinical relevance of Krebs von den Lungen-6 (KL-6) levels in patients with coronavirus
disease 2019 (COVID-19) is unclear. This study aimed to evaluate the correlation between …

[HTML][HTML] Peak value of serum KL-6 may be useful for predicting poor prognosis of severe COVID-19 patients

S Maruyama, Y Nakamori, H Nakano… - European Journal of …, 2022 - Springer
Abstract Background Serum Krebs von den Lungen 6 (KL-6), which reflects alveolar
epithelial injury, was reported to be useful to predict the progression of pneumonitis induced …

[HTML][HTML] Prediction value of KREBS von den lungen-6 (KL-6) biomarker in COVID-19 patients: a systematic review and meta-analysis

M Matuszewski, L Szarpak, Z Rafique… - Journal of Clinical …, 2022 - mdpi.com
The SARS-CoV-2 (COVID-19) pandemic is a major issue that necessitates the use of cutting-
edge disease prediction models. The aim of the study was to assess the existing evidence …

Serum KL-6 level is a useful biomarker for evaluating the severity of coronavirus disease 2019

N Awano, M Inomata, N Kuse, M Tone, K Takada… - Respiratory …, 2020 - Elsevier
Abstract Background Coronavirus disease 2019 (COVID-19) is currently spreading
worldwide. This study examined whether serum Krebs von den Lungen-6 (KL-6) level is a …

Prognostic roles of KL‐6 in disease severity and lung injury in COVID‐19 patients: a longitudinal retrospective analysis

K Deng, Q Fan, Y Yang, X Deng, R He… - Journal of Medical …, 2021 - Wiley Online Library
To investigate the dynamic changes of Krebs von den Lungen‐6 (KL‐6) among patients with
coronavirus disease 2019 (COVID‐19) and the role of KL‐6 as a noninvasive biomarker for …

[HTML][HTML] Usefulness of KL-6 for predicting clinical outcomes in hospitalized COVID-19 patients

M Park, M Hur, H Kim, CH Lee, JH Lee, M Nam - Medicina, 2022 - mdpi.com
Abstract Background: Krebs von den Lungen 6 (KL-6) is a novel biomarker for interstitial
lung disease, and it reflects acute lung injury. We explored the usefulness of KL-6 to predict …

[HTML][HTML] Could KL-6 levels in COVID-19 help to predict lung disease?

AN Frix, L Schoneveld, A Ladang, M Henket… - Respiratory …, 2020 - Springer
Background Coronavirus disease COVID-19 has become a public health emergency of
international concern. Together with the quest for an effective treatment, the question of the …

Serum Krebs von den Lungen-6 levels are associated with mortality and severity in patients with coronavirus disease 2019

T Yamaya, E Hagiwara, T Baba, T Kitayama… - Respiratory …, 2021 - Elsevier
Abstract Background The serum Krebs von den Lungen-6 (KL-6) level is a predictive factor
for acute respiratory distress syndrome (ARDS). The development of ARDS has been …

An in-depth investigation of serum Krebs von den Lungen-6 and other biomarkers in COVID-19 severity and mortality

AP Witarto, AN Rosyid, BS Witarto… - … Archives for Chest …, 2024 - monaldi-archives.org
Krebs von den Lungen-6 (KL-6) is a glycoprotein mainly expressed by type II pneumocytes
and recently known as a lung injury biomarker. However, the number of studies is still …