Endogenous authentic OCT4A proteins directly regulate FOS/AP-1 transcription in somatic cancer cells

Y Zhou, X Chen, B Kang, S She, X Zhang, C Chen… - Cell death & …, 2018 - nature.com
OCT4A is well established as a master transcription factor for pluripotent stem cell (PSC) self-
renewal and a pioneer factor for initiating somatic cell reprogramming, yet its presence and …

Human papillomavirus E7 binds Oct4 and regulates its activity in HPV-associated cervical cancers

T Panayiotou, S Michael, A Zaravinos… - PLoS …, 2020 - journals.plos.org
Octamer binding transcription factor-4 (Oct4), is highly expressed in stem cells and has
indispensable roles in pluripotency and cellular reprogramming. In contrast to other factors …

Oct4 links multiple epigenetic pathways to the pluripotency network

J Ding, H Xu, F Faiola, A Ma'ayan, J Wang - Cell research, 2012 - nature.com
Oct4 is a well-known transcription factor that plays fundamental roles in stem cell self-
renewal, pluripotency, and somatic cell reprogramming. However, limited information is …

Characterization of a novel cell penetrating peptide derived from human Oct4

E Harreither, HA Rydberg, HL Åmand, V Jadhav… - Cell Regeneration, 2014 - Springer
Background Oct4 is a transcription factor that plays a major role for the preservation of the
pluripotent state in embryonic stem cells as well as for efficient reprogramming of somatic …

[PDF][PDF] An expanded Oct4 interaction network: implications for stem cell biology, development, and disease

M Pardo, B Lang, L Yu, H Prosser, A Bradley, MM Babu… - Cell stem cell, 2010 - cell.com
The transcription factor Oct4 is key in embryonic stem cell identity and reprogramming.
Insight into its partners should illuminate how the pluripotent state is established and …

[PDF][PDF] Hooking up with Oct4

IR Lemischka - Cell stem cell, 2010 - cell.com
The transcription factor Oct4 plays a central role in controlling the undifferentiated state of
embryonic and induced pluripotent stem cells. Two complementary papers in this issue of …

[PDF][PDF] Oct4 expression is not required for mouse somatic stem cell self-renewal

CJ Lengner, FD Camargo, K Hochedlinger… - Cell stem cell, 2007 - cell.com
The Pou domain containing transcription factor Oct4 is a well-established regulator of
pluripotency in the inner cell mass of the mammalian blastocyst as well as in embryonic …

Embryonic stem cell markers expression in cancers

M Schoenhals, A Kassambara, J De Vos… - Biochemical and …, 2009 - Elsevier
The transcription factors Oct4 and Sox2 are highly expressed in embryonic stem (ES) cells.
In conjunction with Klf4 and c-Myc, their over-expression can induce pluripotency in both …

OCT4 spliced variants are differentially expressed in human pluripotent and nonpluripotent cells

Y Atlasi, SJ Mowla, SAM Ziaee, PJ Gokhale… - Stem …, 2008 - academic.oup.com
OCT4 is a master regulator of self-renewal in embryonic stem cells and can potentially
encode two spliced variants, designated OCT4A and OCT4B. We have examined the …

Absence of OCT4 expression in somatic tumor cell lines

T Cantz, G Key, M Bleidiβel, L Gentile, DW Han… - Stem …, 2008 - academic.oup.com
The POU-domain transcription factor OCT4 is associated with the pluripotent state of cells
comprising the inner cell mass of pre-implantation embryos and has been known to play a …