[HTML][HTML] Epigenetic reprogramming of epithelial-mesenchymal transition promotes ferroptosis of head and neck cancer

J Lee, JH You, MS Kim, JL Roh - Redox biology, 2020 - Elsevier
Ferroptosis is a newly defined form of cell death induced by iron-dependent accumulation of
lethal lipid peroxidation. Ferroptosis represent a therapeutic strategy to suppress therapy …

[HTML][HTML] Ferroptosis and EMT: key targets for combating cancer progression and therapy resistance

Y Ren, X Mao, H Xu, Q Dang, S Weng, Y Zhang… - Cellular and Molecular …, 2023 - Springer
Iron-dependent lipid peroxidation causes ferroptosis, a form of regulated cell death. Crucial
steps in the formation of ferroptosis include the accumulation of ferrous ions (Fe2+) and lipid …

Crosstalk between ferroptosis and the epithelial-mesenchymal transition: Implications for inflammation and cancer therapy

N Ebrahimi, S Adelian, S Shakerian… - Cytokine & growth factor …, 2022 - Elsevier
Both genomic instability and the presence of chronic inflammation are involved in
carcinogenesis and tumor progression. These alterations predispose the cancer cells to …

[HTML][HTML] Ferroptosis-mediated crosstalk in the tumor microenvironment implicated in cancer progression and therapy

Y Liu, C Duan, R Dai, Y Zeng - Frontiers in cell and developmental …, 2021 - frontiersin.org
Ferroptosis is a recently recognized form of non-apoptotic regulated cell death and usually
driven by iron-dependent lipid peroxidation and has arisen to play a significant role in …

Ferroptosis regulation by methylation in cancer

M Hao, Y Jiang, Y Zhang, X Yang, J Han - Biochimica et Biophysica Acta …, 2023 - Elsevier
Epigenetic regulation plays a critical role in cancer development and progression.
Methylation is an important epigenetic modification that influences gene expression by …

[HTML][HTML] Ferroptosis: a new road towards cancer management

I Bano, P Horky, SQ Abbas, M Majid, AHM Bilal, F Ali… - Molecules, 2022 - mdpi.com
Ferroptosis is a recently described programmed cell death mechanism that is characterized
by the buildup of iron (Fe)-dependent lipid peroxides in cells and is morphologically …

[HTML][HTML] Ferroptosis in cancer: From molecular mechanisms to therapeutic strategies

Q Zhou, Y Meng, D Li, L Yao, J Le, Y Liu… - … and Targeted Therapy, 2024 - nature.com
Ferroptosis is a non-apoptotic form of regulated cell death characterized by the lethal
accumulation of iron-dependent membrane-localized lipid peroxides. It acts as an innate …

[HTML][HTML] Targeting ferroptosis for cancer therapy: exploring novel strategies from its mechanisms and role in cancers

M Jiang, M Qiao, C Zhao, J Deng, X Li… - … lung cancer research, 2020 - ncbi.nlm.nih.gov
Ferroptosis is a novel form of non-apoptotic regulated cell death (RCD), with distinct
characteristics and functions in physical conditions and multiple diseases such as cancers …

[HTML][HTML] Ferroptosis: a novel regulated cell death participating in cellular stress response, radiotherapy, and immunotherapy

X Zheng, X Jin, F Ye, X Liu, B Yu, Z Li, T Zhao… - … Hematology & Oncology, 2023 - Springer
Background Ferroptosis is a regulated cell death mode triggered by iron-dependent toxic
membrane lipid peroxidation. As a novel cell death modality that is morphologically and …

[HTML][HTML] Targeting ferroptosis pathway to combat therapy resistance and metastasis of cancer

X Liu, Y Zhang, X Wu, F Xu, H Ma, M Wu… - Frontiers in …, 2022 - frontiersin.org
Ferroptosis is an iron-dependent regulated form of cell death caused by excessive lipid
peroxidation. This form of cell death differed from known forms of cell death in morphological …