Ferroptosis, a new form of cell death, and its relationships with tumourous diseases

H Yu, P Guo, X Xie, Y Wang… - Journal of cellular and …, 2017 - Wiley Online Library
Ferroptosis is a newly discovered type of cell death that differs from traditional apoptosis and
necrosis and results from iron‐dependent lipid peroxide accumulation. Ferroptotic cell death …

Ferroptosis meets cell–cell contacts

C Dietrich, TG Hofmann - Cells, 2021 - mdpi.com
Ferroptosis is a regulated form of cell death characterized by iron dependency and
increased lipid peroxidation. Initially assumed to be selectively induced in tumour cells …

[HTML][HTML] Targeted p53 on small-molecules-induced ferroptosis in cancers

W Zhang, C Gai, D Ding, F Wang, W Li - Frontiers in oncology, 2018 - frontiersin.org
Ferroptosis is a type of programmed cell death characterized by the accumulation of lipid
reactive oxygen species (L-ROS) driven by the oxidative degeneration of lipids in an iron …

Novel insights on targeting ferroptosis in cancer therapy

S Zuo, J Yu, H Pan, L Lu - Biomarker Research, 2020 - Springer
Ferroptosis belongs to a novel form of regulated cell death. It is characterized by iron
dependence, destruction of intracellular redox balance and non-apoptosis. And cellular …

Ferroptosis and the bidirectional regulatory factor p53

R Xu, W Wang, W Zhang - Cell Death Discovery, 2023 - nature.com
Ferroptosis is a type of regulated cell death characterized by iron-mediated lipid
peroxidation, in contrast with apoptosis, autophagy, and necrosis. It can be triggered by …

[HTML][HTML] Ferroptosis: a promising target for cancer immunotherapy

LL Sun, DL Linghu, MC Hung - American journal of cancer …, 2021 - ncbi.nlm.nih.gov
Ferroptosis is a recently recognized type of programmed cell death and emerges to play an
important role in cancer biology and therapies. This unique form of cell death, characterized …

Mechanisms of ferroptosis and relations with regulated cell death: a review

P Lei, T Bai, Y Sun - Frontiers in physiology, 2019 - frontiersin.org
Ferroptosis is a newly identified form of nonapoptotic regulated cell death (RCD)
characterized by iron-dependent accumulation of lipid peroxides. It is morphologically and …

Emerging mechanisms and disease relevance of ferroptosis

BR Stockwell, X Jiang, W Gu - Trends in cell biology, 2020 - cell.com
Cell death is an essential feature of development in multicellular organisms, a critical driver
of degenerative diseases, and can be harnessed for treating some cancers. Understanding …

Ferroptosis in gastrointestinal cancer: from mechanisms to implications

R Zhang, R Kang, D Tang - Cancer Letters, 2023 - Elsevier
Ferroptosis is a form of regulated cell death that is initiated by excessive lipid peroxidation
that results in plasma membrane damage and the release of damage-associated molecular …

Ferroptosis, radiotherapy, and combination therapeutic strategies

G Lei, C Mao, Y Yan, L Zhuang, B Gan - Protein & cell, 2021 - academic.oup.com
Ferroptosis, an iron-dependent form of regulated cell death driven by peroxidative damages
of polyunsaturated-fatty-acid-containing phospholipids in cellular membranes, has recently …