Mechanisms of neuropathic pain

FT Nickel, F Seifert, S Lanz, C Maihöfner - European …, 2012 - Elsevier
Neuropathic pain is a disease of global burden. Its symptoms include spontaneous and
stimulus-evoked painful sensations. Several maladaptive mechanisms underlying these …

Dissecting out mechanisms responsible for peripheral neuropathic pain: implications for diagnosis and therapy

CJ Woolf - Life sciences, 2004 - Elsevier
Peripheral neuropathic pain, that clinical pain syndrome associated with lesions to the
peripheral nervous system, is characterized by positive and negative symptoms. Positive …

Pathophysiological mechanisms of neuropathic pain

A Truini, G Cruccu - Neurological Sciences, 2006 - Springer
It is largely acknowledged that multiple and complex pathophysiological mechanisms may
be at play in neuropathic pain. This short review summarises the current understanding of …

Mechanisms of disease: neuropathic pain—a clinical perspective

R Baron - Nature clinical practice Neurology, 2006 - nature.com
Neuropathic pain syndromes—pain after a lesion or disease of the peripheral or central
nervous system—are clinically characterized by spontaneous and evoked types of pain …

Neuropathic pain: models and mechanisms

JM Boyce-Rustay, MF Jarvis - Current pharmaceutical design, 2009 - ingentaconnect.com
Advances in the characterization of pain signaling in recent years indicate that distinct
neurophysiological and neurochemical mechanisms contribute to pain arising from injury to …

Mechanisms of neuropathic pain

JN Campbell, RA Meyer - Neuron, 2006 - cell.com
Neuropathic pain refers to pain that originates from pathology of the nervous system.
Diabetes, infection (herpes zoster), nerve compression, nerve trauma," channelopathies," …

Peripheral mechanisms of neuropathic pain—the role of neuronal and non-neuronal interactions and their implications for topical treatment of neuropathic pain

M Kocot-Kępska, R Zajączkowska, J Mika… - Pharmaceuticals, 2021 - mdpi.com
Neuropathic pain in humans arises as a consequence of injury or disease of somatosensory
nervous system at peripheral or central level. Peripheral neuropathic pain is more common …

Translational neuropathic pain research: a clinical perspective

D Bouhassira, N Attal - Neuroscience, 2016 - Elsevier
Neuropathic pain encompasses a broad range of conditions associated with a lesion or
disease of the peripheral or central somatosensory system and its prevalence in the general …

Neuropathic pain: from mechanisms to treatment

NB Finnerup, R Kuner, TS Jensen - Physiological reviews, 2021 - journals.physiology.org
Neuropathic pain caused by a lesion or disease of the somatosensory nervous system is a
common chronic pain condition with major impact on quality of life. Examples include …

Translational investigation and treatment of neuropathic pain

B Xu, G Descalzi, HR Ye, M Zhuo… - Molecular …, 2012 - journals.sagepub.com
Neuropathic pain develops from a lesion or disease affecting the somatosensory system.
Translational investigations of neuropathic pain by using different animal models reveal that …