To date, research into the biological processes and molecular mechanisms associated with
endometrial receptivity and embryo implantation has been a focus of attention, whereas the …

The human endometrium is a highly dynamic tissue that is cyclically shed, repaired,
regenerated and remodelled, primarily under the orchestration of oestrogen and …

Our understanding of the mechanisms of the actions of oestrogens and progestins have
evolved from the simple concept of nuclear receptor-mediated regulation of transcription to a …

Endometriosis is a complex and challenging disease that involves aberrant adhesion,
growth, and progression of endometrial tissues outside of the uterine cavity, and there is …

Background In the endometrium the steroid hormone progesterone (P), acting through its
nuclear receptors, regulates the expression of specific target genes and gene networks …

The text herein is an overview of hormone receptor dynamics in human endometrium as
presented at the Society for Gynecologic Investigation Summit on Implantation. It is not an in …

Background It has been well established that endometriosis is an estrogen‐dependent
disease. Although the exact pathogenesis of the disease is still unclear, it is known to be …

Intensive research work has been performed to better understand the regulation of the
endometrium and its clinical implications to improve implantation. Although many proteins …

In the healthy endometrium, progesterone and estrogen signaling coordinate in a tightly
regulated, dynamic interplay to drive a normal menstrual cycle and promote an embryo …

The endometrium is the site of implantation and pregnancy. Preparation for this important
biological event relies primarily on progesterone, which takes the estrogen-primed …