To assess the mutational status of BRAF in FVPTC, we directly sequenced the genomic DNA
of 30 primary FVPTC samples. BRAF mutations were found in only 4 (13%) tumors. We also …

Context: Mutations in BRAF are rare in the follicular variant of papillary thyroid carcinoma
(FV-PTC). Objective: We identified and functionally characterized a novel T599I-VKSR (600 …

An activating mutation in the BRAF gene is the most common genetic alteration in papillary
thyroid carcinomas (PTCs). The mutation in PTCs is almost a c. 1799T> A transversion …

Introduction Activating mutations of the BRAF oncogene are frequently detected in papillary
thyroid carcinoma (PTC) and have been associated with a worse prognosis. The amino acid …

Activating mutations of the BRAF gene are the most common genetic alterations in papillary
thyroid carcinomas (PTCs) and the T1799A transversion, resulting in BRAF V600E …

A common mutation in the BRAF gene, comprising the T1799A nucleotide transversion,
which leads to the V600E amino acid substitution in the BRAF protein, has been observed in …

BRAF gene mutations have been frequently detected in papillary thyroid carcinoma (PTC).
Moreover, there is a close association between the type of mutation and the PTC histotype …

Background: A single hotspot mutation at nucleotide 1799 of the BRAF gene has been
identified as the most common genetic event in papillary thyroid carcinoma (PTC), with a …

The BRAF point mutation is the most common genetic event in papillary thyroid carcinoma
(PTC), occurring in 29-69% of such tumors. The V600E mutation accounts for up to 95% of …

Background: BRAF mutations, the most common genetic alteration associated with papillary
thyroid carcinoma (PTC), have never been associated with follicular thyroid carcinoma (FTC) …