We evaluated the significance of aberrant DNA methyltransferase 1 (DNMT1) protein
expression during gastric carcinogenesis. The protein expression of DNMT1, Muc2, human …

Abstract DNA methyltransferase (DNMT) 1, DNMT3A and DNMT3B, which affect promoter
CpG methylation status, play a significant role in cancer development. Little is known …

We evaluated the significance of aberrant DNA methyltransferase expression in human
carcinogenesis by examining 32 colorectal and 34 stomach cancers. Levels of mRNAs …

This study investigates the varied expression of DNA methyltransferase (DNMT) proteins in
gastric cancer (GC) and their relationship with the biological behavior of the tissues …

Aberrant DNA methylation has been shown to play an important role during multistage
carcinogenesis in various human organs. The aim of the present study was to evaluate the …

Somatic changes in CpG dinucleotide methylation occur quite commonly in human cancer
cell DNA. Relative to DNA from normal human colonic cells, DNA from human colorectal …

To evaluate the significance of alterations in DNA methylation during multistage
carcinogenesis of the pancreas, tissue samples of 13 peripheral pancreatic duct epithelia …

Aberrant DNA methylation and increased expression of DNA methyltransferases (DNMTs)
are features of tumor cells. To investigate roles for DNMTs during hepatocarcinogenesis, we …

Alteration of DNA methylation is one of the most consistent epigenetic changes in human
cancers. DNA methyltransferase (DNMT) 1 is a major enzyme that determines genomic …

Alterations of DNA methylation are one of the most consistent epigenetic changes in human
cancers. Human cancers generally show global DNA hypomethylation accompanied by …