Involvement of Bcl-2 family proteins in germ cell apoptosis during testicular development in the rat and pro-survival effect of stem cell factor on germ cells in vitro

W Yan, J Suominen, M Samson, B Jégou… - Molecular and cellular …, 2000 - Elsevier
A large part of germ cells die apoptotically during testicular development in rodents. In the
present study, a wave of germ cell apoptosis was observed between days 10 and 30 of …

[PDF][PDF] Germ cell apoptosis in men with complete and incomplete spermiogenesis failure.

J Tesarik, E Greco, P Cohen-Bacrie… - Molecular human …, 1998 - Citeseer
Germ cell apoptosis was evaluated in 11 men suffering from nonobstructive azoospermia
and enrolled in a spermatid conception programme. In six of these patients, round …

Spontaneous germ cell apoptosis in humans: evidence for ethnic differences in the susceptibility of germ cells to programmed cell death

AP Sinha Hikim, C Wang, Y Lue… - The Journal of …, 1998 - academic.oup.com
Spontaneous death of certain classes of germ cells has been shown to be a constant feature
of normal spermatogenesis in a variety of mammalian species, including the human. Recent …

Clinical aspects of male germ cell apoptosis during testis development and spermatogenesis

L Dunkel, V Hirvonen, K Erkkilä - Cell Death & Differentiation, 1997 - nature.com
Apoptosis appears to have an essential role in the control of germ cell number in testes.
During spermatogenesis germ cell deletion has been estimated to result in the loss of up to …

Increased apoptosis occurring during the first wave of spermatogenesis is stage-specific and primarily affects midpachytene spermatocytes in the rat testis

K Jahnukainen, D Chrysis, M Hou… - Biology of …, 2004 - academic.oup.com
The physiological apoptosis that occurs in immature testis appears to be necessary for the
maturation of this tissue. Thus, inhibition of the early apoptotic wave associated with the first …

Apoptosis and necrosis in human ejaculated spermatozoa

C Lachaud, J Tesarik, ML Cañadas… - Human …, 2004 - academic.oup.com
BACKGROUND: Features of both apoptosis and necrosis have been reported in ejaculated
human spermatozoa. This study examines the relative contribution of these two modes of …

In situ end-labeling of human testicular tissue demonstrates increased apoptosis in conditions of abnormal spermatogenesis

WW Lin, DJ Lamb, TM Wheeler, LI Lipshultz, ED Kim - Fertility and Sterility, 1997 - Elsevier
Objective: To determine, using an in situ end-labeling technique, whether the frequency of
apoptosis is increased in testis biopsy specimens that demonstrate abnormal …

Apoptosis in human ejaculated sperm cells (notulae seminologicae 9).

B Baccetti, G Collodel, P Piomboni - Journal of submicroscopic …, 1996 - europepmc.org
In this work we apply the Hoechst 33258 DNA staining, the TUNEL procedure and
conventional electron microscopy to study the ejaculate of fertile and infertile men, in order …

[引用][C] Apoptosis of male germ cells, a generalized or a cell type-specific phenomenon?

A Bartke - Endocrinology, 1995 - academic.oup.com
Histological studies by Clermont and his colleagues in the 50s and 60s (1, 2) form a basis of
the current understanding of the dynamics of spermatogenesis and its hormonal control …

Male germ cell apoptosis: regulation and biology

C Shaha, R Tripathi, DP Mishra - … Transactions of the …, 2010 - royalsocietypublishing.org
Cellular apoptosis appears to be a constant feature in the adult testis and during early
development. This is essential because mammalian spermatogenesis is a complex process …