Early in postnatal life, the first wave of spermatogenesis is accompanied by an initial wave of
germ cell apoptosis. This may reflect an adjustment in the number of germ cells that can be …

Apoptosis is the main cause of primordial germ cell and oocyte degeneration in the
developing fetal ovary. In this study we examined by immunohistochemistry and …

This review examines experimental models of Sertoli cell injury resulting in germ cell
apoptosis. Since germ cells exist in an environment created by Sertoli cells, paracrine …

Recent studies have demonstrated apoptotic DNA fragmentation in the testis of immature
rats deprived of gonadotropins. However, the exact cell type undergoing apoptosis during …

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The relationship between human sperm maturity and apoptosis is of interest because of the
persistence of immature sperm in ejaculates in spite of various apoptotic processes during …

In this study we examined the possibility that regular or circadian fluctuations occur in the
frequency of spontaneous spermatogonial apoptosis. Apoptosis of A2, A3 and A4 type …

Programmed cell death is an evolutionarily conserved cell death process that plays a major
role during normal development and homeostasis. In many cases, the ordered execution of …

The seminiferous epithelium is a highly proliferating tissue in which germ cell" degeneration"
is a constant feature. Recent data based on morphological analysis have shown that …

Since the cloning of the bcl-2 gene in 1985, considerable progress has been made in
elucidating the function of Bcl-2 and related proteins in controlling apoptosis. Although much …