Programmed cell death in the germline
JS Baum, JPS George, K McCall - Seminars in Cell & Developmental …, 2005 - Elsevier
In many organisms, programmed cell death of germ cells is required for normal
development. This often occurs through highly conserved events including the transfer of …
development. This often occurs through highly conserved events including the transfer of …
Gonadal cell apoptosis.
AJ Hsueh, K Eisenhauer, SY Chun… - Recent Progress in …, 1996 - europepmc.org
Apoptosis is an important cellular process by which superfluous or unwanted cells are
deleted from an organism during tissue remodeling and differentiation. Recent studies have …
deleted from an organism during tissue remodeling and differentiation. Recent studies have …
An elevated bax/bcl-2 ratio corresponds with the onset of prostate epithelial cell apoptosis
The prostate gland in adult male rats is highly dependent on androgenic steroids. Castration
initiates the regression of this tissue through a process involving the loss of the vast majority …
initiates the regression of this tissue through a process involving the loss of the vast majority …
Autonomous cell death of mouse male germ cells during fetal and postnatal period
RA Wang, PK Nakane, T Koji - Biology of reproduction, 1998 - academic.oup.com
Germ cell degeneration is common in mammalian testes during the developmental as well
as the adult period. To investigate the extent and mechanisms of male germ cell death …
as the adult period. To investigate the extent and mechanisms of male germ cell death …
Bcl-2 overexpression results in reciprocal downregulation of Bcl-XL and sensitizes human testicular germ cell tumours to chemotherapy-induced apoptosis
EL Arriola, AM Rodriguez-Lopez, JA Hickman… - Oncogene, 1999 - nature.com
Testicular germ cell tumours are hypersentive to chemotherapy and cell lines derived from
these tumours are chemosensitive in vitro. We have previously shown that these cell lines …
these tumours are chemosensitive in vitro. We have previously shown that these cell lines …
[PDF][PDF] Apoptosis precedes detachment of germ cells from the seminiferous epithelium after hormone suppression by short-term oestradiol treatment of rats
J Blanco-Rodriguez, C Martinez-Garcia - Int J Androl, 1998 - Wiley Online Library
Spermatogenesis is a highly synchronized process in which FSH and testosterone are
considered the major regulators. Nevertheless, the mechanism by which these hormones …
considered the major regulators. Nevertheless, the mechanism by which these hormones …
Detection of apoptotic alterations in sperm in subfertile patients and their correlations with sperm quality
BACKGROUND: The aim of the present study was to define the effect of apoptosis on sperm
quality and function. METHODS: The apoptotic features in sperm were assessed in 60 …
quality and function. METHODS: The apoptotic features in sperm were assessed in 60 …
Spermatogonial stem cells
DG De Rooij, JA Grootegoed - Current opinion in cell biology, 1998 - Elsevier
The mammalian seminiferous epithelium consists of a highly complex yet well-organized
cell population, with germ cells in mitosis and meiosis and postmeiotic cells undergoing …
cell population, with germ cells in mitosis and meiosis and postmeiotic cells undergoing …
Apoptosis is physiologically restricted to a specialized cytoplasmic compartment in rat spermatids
J Blanco-Rodríguez… - Biology of reproduction, 1999 - academic.oup.com
Cytoplasmic caudal tags of maturing spermatids condense and are detached from the
spermatidal cells just before the spermatids are released as spermatozoa. The detached …
spermatidal cells just before the spermatids are released as spermatozoa. The detached …
Significance of apoptosis in the temporal and stage-specific loss of germ cells in the adult rat after gonadotropin deprivation
AP Sinha Hikim, TB Rajavashisth, IS Hikim… - Biology of …, 1997 - academic.oup.com
The major objectives of the present study were to document the temporal and stage-specific
acceleration of germ cell apoptosis in adult rats after selective suppression of pituitary …
acceleration of germ cell apoptosis in adult rats after selective suppression of pituitary …